Telmisartan prevents the glitazone-induced weight gain without interfering with its insulin-sensitizing properties
- Zanchi, Anne Division of Nephrology and Department of Medicine, CHUV and University of Lausanne, Switzerland
- Dulloo, Abdul G. Division of Physiology, University of Fribourg, Switzerland
- Perregaux, Christine Division of Nephrology and Department of Medicine, CHUV and University of Lausanne, Switzerland
- Montani, Jean-Pierre Division of Physiology, University of Fribourg, Switzerland
- Burnier, Michel Division of Nephrology and Department of Medicine, CHUV and University of Lausanne, Switzerland
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20.03.2007
Published in:
- American Journal of Physiology - Endocrinology and Metabolism. - 2007, vol. 293, p. E91-E95
English
Glitazones are peroxisome proliferator-activated receptor (PPAR)-Γ agonists with powerful insulin-sensitizing properties. They promote the development of metabolically active adipocytes that can lead to a substantial gain in fat mass. Telmisartan is an ANG II type 1 receptor antagonist with partial PPAR-Γ agonistic properties. Recently, telmisartan has been reported to prevent weight gain and... Show more…
- Faculty
- Faculté des sciences et de médecine
- Department
- Département de Médecine
- Language
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- English
- Classification
- Medicine
- License
- License undefined
- Identifiers
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- RERO DOC 8152
- DOI 10.1152/ajpendo.00024.2007
- Persistent URL
- https://folia.unifr.ch/unifr/documents/300302