Telmisartan prevents the glitazone-induced weight gain without interfering with its insulin-sensitizing properties
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Zanchi, Anne
Division of Nephrology and Department of Medicine, CHUV and University of Lausanne, Switzerland
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Dulloo, Abdul G.
Division of Physiology, University of Fribourg, Switzerland
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Perregaux, Christine
Division of Nephrology and Department of Medicine, CHUV and University of Lausanne, Switzerland
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Montani, Jean-Pierre
Division of Physiology, University of Fribourg, Switzerland
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Burnier, Michel
Division of Nephrology and Department of Medicine, CHUV and University of Lausanne, Switzerland
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Published in:
- American Journal of Physiology - Endocrinology and Metabolism. - 2007, vol. 293, p. E91-E95
English
Glitazones are peroxisome proliferator-activated receptor (PPAR)-Γ agonists with powerful insulin-sensitizing properties. They promote the development of metabolically active adipocytes that can lead to a substantial gain in fat mass. Telmisartan is an ANG II type 1 receptor antagonist with partial PPAR-Γ agonistic properties. Recently, telmisartan has been reported to prevent weight gain and... Show more…
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Faculty
- Faculté des sciences et de médecine
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Department
- Département de Médecine
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Language
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Classification
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Medicine
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License
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License undefined
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Identifiers
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Persistent URL
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https://folia.unifr.ch/unifr/documents/300302