Journal article

Ethanolaminephosphate Side Chain Added to Glycosylphosphatidylinositol (GPI) Anchor by Mcd4p Is Required for Ceramide Remodeling and Forward Transport of GPI Proteins from Endoplasmic Reticulum to Golgi

  • Zhu, Yonghua Institute of Live Science and Biotechnology, Hunan University, Changsha, China
  • Vionnet, Christine Department of Medicine, Biochemistry Unit, University of Fribourg, Switzerland
  • Conzelmann, Andreas Department of Medicine, Biochemistry Unit, University of Fribourg, Switzerland
    16.05.2006
Published in:
  • Journal of Biological Chemistry. - 2006, vol. 281, no. 29, p. 19830-19839
English Glycosylphosphatidylinositol (GPI) anchors of mammals as well as yeast contain ethanolaminephosphate side chains on the α1–4- and the α1–6-linked mannoses of the anchor core structure (protein-CO-NH-(CH₂)₂-PO₄-6Manα1–2Manα1–6Manα1–4GlcNH₂-inositol-PO₄-lipid). In yeast, the ethanolaminephosphate on the α1–4-linked mannose is added during the biosynthesis of the GPI lipid by Mcd4p. <i>MCD4</i>... Show more…
Faculty
Faculté des sciences et de médecine
Department
Département de Biologie
Language
  • English
Classification
Biology
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/300234