Journal article

Dual targeting of a single tRNATrp requires two different tryptophanyl-tRNA synthetases in Trypanosoma brucei

  • Charrière, Fabien Department of Biology Cell and Developmental Biology, University of Fribourg, Switzerland
  • Helgadóttir, Sunna Departments of Molecular Biophysics and Biochemistry, Yale University, New Haven, USA
  • Horn, Elke K. Department of Biology Cell and Developmental Biology, University of Fribourg, Switzerland
  • Söll, Dieter Departments of Molecular Biophysics and Biochemistry, Yale University, New Haven, USA - Department of Chemistry, Yale University, New Haven, USA
  • Schneider, André Department of Biology Cell and Developmental Biology, University of Fribourg, Switzerland
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    2006
Published in:
  • Proceedings of the National Academy of Sciences of the United States of America. - 2006, vol. 103, p. 6847-6852
English The mitochondrion of <i>Trypanosoma brucei</i> does not encode any tRNAs. This deficiency is compensated for by the import of a small fraction of nearly all of its cytosolic tRNAs. Most trypanosomal aminoacyl-tRNA synthetases are encoded by single-copy genes, suggesting the use of the same enzyme in the cytosol and mitochondrion. However, the <i>T. brucei</i> genome contains two distinct genes... Show more…
Faculty
Faculté des sciences
Department
Biologie
Language
  • English
Classification
Biology
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/300110