Primate adult brain cell autotransplantation, a new tool for brain repair ?
- Brunet, Jean-François Department of Neurosurgery, Lausanne University Hospital, Switzerland
- Rouiller, Eric M. Institute of Physiology, Department of Medicine, University of Fribourg, Switzerland
- Wannier, Thierry Institute of Physiology, Department of Medicine, University of Fribourg, Switzerland
- Villemure, Jean-Guy Department of Neurosurgery, Lausanne University Hospital, Switzerland
- Bloch, Jocelyne Department of Neurosurgery, Lausanne University Hospital, Switzerland
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23.05.2005
Published in:
- Experimental Neurology. - 2005, vol. 196, no. 1, p. 195-198
English
If successful, autologous brain cell transplantation is an attractive approach to repair lesions and restore function of the central nervous system. We demonstrate that monkey adult brain cells obtained from cortical biopsy and kept in culture for 4 weeks exhibit neural progenitor characteristics. After reimplantation into a lesion area of the donor cerebral cortex, these cells can successfully survive and acquire neuronal characteristics over time. These results open new perspectives in the field of brain repair and may lead to future clinical applications.
- Faculty
- Faculté des sciences et de médecine
- Department
- Département de Médecine
- Language
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- English
- Classification
- Biological sciences
- License
- License undefined
- Identifiers
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- RERO DOC 5431
- DOI 10.1016/j.expneurol.2005.04.005
- Persistent URL
- https://folia.unifr.ch/unifr/documents/300081
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