Primate adult brain cell autotransplantation, a new tool for brain repair ?
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Brunet, Jean-François
Department of Neurosurgery, Lausanne University Hospital, Switzerland
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Rouiller, Eric M.
Institute of Physiology, Department of Medicine, University of Fribourg, Switzerland
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Wannier, Thierry
Institute of Physiology, Department of Medicine, University of Fribourg, Switzerland
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Villemure, Jean-Guy
Department of Neurosurgery, Lausanne University Hospital, Switzerland
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Bloch, Jocelyne
Department of Neurosurgery, Lausanne University Hospital, Switzerland
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Published in:
- Experimental Neurology. - 2005, vol. 196, no. 1, p. 195-198
English
If successful, autologous brain cell transplantation is an attractive approach to repair lesions and restore function of the central nervous system. We demonstrate that monkey adult brain cells obtained from cortical biopsy and kept in culture for 4 weeks exhibit neural progenitor characteristics. After reimplantation into a lesion area of the donor cerebral cortex, these cells can successfully survive and acquire neuronal characteristics over time. These results open new perspectives in the field of brain repair and may lead to future clinical applications.
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Faculty
- Faculté des sciences et de médecine
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Department
- Département de Médecine
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Language
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Classification
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Biological sciences
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License
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License undefined
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Identifiers
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Persistent URL
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https://folia.unifr.ch/unifr/documents/300081
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