Journal article

Primate adult brain cell autotransplantation, a new tool for brain repair ?

  • Brunet, Jean-François Department of Neurosurgery, Lausanne University Hospital, Switzerland
  • Rouiller, Eric M. Institute of Physiology, Department of Medicine, University of Fribourg, Switzerland
  • Wannier, Thierry Institute of Physiology, Department of Medicine, University of Fribourg, Switzerland
  • Villemure, Jean-Guy Department of Neurosurgery, Lausanne University Hospital, Switzerland
  • Bloch, Jocelyne Department of Neurosurgery, Lausanne University Hospital, Switzerland
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    23.05.2005
Published in:
  • Experimental Neurology. - 2005, vol. 196, no. 1, p. 195-198
English If successful, autologous brain cell transplantation is an attractive approach to repair lesions and restore function of the central nervous system. We demonstrate that monkey adult brain cells obtained from cortical biopsy and kept in culture for 4 weeks exhibit neural progenitor characteristics. After reimplantation into a lesion area of the donor cerebral cortex, these cells can successfully survive and acquire neuronal characteristics over time. These results open new perspectives in the field of brain repair and may lead to future clinical applications.
Faculty
Faculté des sciences et de médecine
Department
Département de Médecine
Language
  • English
Classification
Biology
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/300081
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