Journal article

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Adaptive coding of reward value by dopamine neurons

  • Tobler, Philippe N. Department of Anatomy, University of Cambridge, UK, - Institute of Physiology, University of Fribourg, Switzerland
  • Fiorillo, Christopher D. Department of Anatomy, University of Cambridge, UK, - Institute of Physiology, University of Fribourg, Switzerland - Department of Biology, Stanford University, USA
  • Schultz, Wolfram Department of Anatomy, University of Cambridge, UK, - Institute of Physiology, University of Fribourg, Switzerland
    2005
Published in:
  • Science. - 2001, vol. 307, no. 5715, p. 1642-1645
English It is important for animals to estimate the value of rewards as accurately as possible. Because the number of potential reward values is very large, it is necessary that the brain's limited resources be allocated so as to discriminate better among more likely reward outcomes at the expense of less likely outcomes. We found that midbrain dopamine neurons rapidly adapted to the information provided by reward-predicting stimuli. Responses shifted relative to the expected reward value, and the gain adjusted to the variance of reward value. In this way, dopamine neurons maintained their reward sensitivity over a large range of reward values.
Faculty
Faculté des sciences et de médecine
Department
Département de Médecine
Language
  • English
Classification
Biology
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/300070
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