Electrostatic control on endo/exo selectivity in ionic cycloaddition
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Tamilmani, Venkatachalam
Department of Chemistry, University of Fribourg, Switzerland - Department of Chemistry, Bharathidasan University, Tiruchirappalli, India
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Daul, Claude
Department of Chemistry, University of Fribourg, Switzerland
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Venuvanalingam, P.
Department of Chemistry, Bharathidasan University, Tiruchirappalli, India
Published in:
- Chemical Physics Letters. - 2005, vol. 416, no. 4-6, p. 354-357
English
DFT method has been used in combination with various basis sets to model the ionic cycloaddition of cationic heteroaromatic diene, 2,3-dimethylisoquinoliniuim ion with cyclopentadiene with a view to understand the factors that influence the stereochemical outcome of the reaction. Calculations show that this reaction is an inverse electron demand type reaction and it passes through highly asynchronous transition states and mainly electrostatic repulsion govern the endo/exo selectivity of the reaction. Endo TS is more destabilized than exo TS due to repulsion between positive charges delocalized over the two reacting partners in the transition state and hence, exo adduct is more preferred than endo adduct in total agreement with experiment.
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Faculty
- Faculté des sciences et de médecine
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Department
- Département de Chimie
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Language
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Classification
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Chemistry
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License
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License undefined
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Identifiers
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Persistent URL
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https://folia.unifr.ch/unifr/documents/300062
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