Journal article

Endothelial nitric oxide synthase gene transfer restores endothelium–dependent relaxations and attenuates lesion formation in carotid arteries in apolipoprotein E–deficient mice

  • Mujynya-Ludunge, Kathi Division of Cardiology, Faculty of Biology and Medicine, University of Lausanne, Switzerland - Institute of Microbiology, Faculty of Biology and Medicine, University of Lausanne, Switzerland
  • Viswambharan, Hema Physiology Unit, Department of Medicine, University of Fribourg, Switzerland
  • Driscoll, Robert Division of Cardiology, Faculty of Biology and Medicine, University of Lausanne, Switzerland
  • Ming, Xiu-Fen Physiology Unit, Department of Medicine, University of Fribourg, Switzerland
  • Segesser, Ludwig K. von Division of Cardiovascular Surgery, Faculty of Biology and Medicine, University of Lausanne, Switzerland
  • Kappenberger, Lukas Division of Cardiology, Faculty of Biology and Medicine, University of Lausanne, Switzerland
  • Yang, Zhihong Physiology Unit, Department of Medicine, University of Fribourg, Switzerland
  • Vassalli, Giuseppe Division of Cardiology, Faculty of Biology and Medicine, University of Lausanne, Switzerland - Institute of Microbiology, Faculty of Biology and Medicine, University of Lausanne, Switzerland
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    24.11.2004
Published in:
  • Basic Research in Cardiology. - 2005, vol. 100(2), p. 102
English Nitric oxide (NO) and monocyte chemoattractant protein–1 (MCP-1) exert partly opposing effects in vascular biology. NO plays pleiotropic vasoprotective roles including vasodilation and inhibition of platelet aggregation, smooth muscle cell proliferation, and endothelial monocyte adhesion, the last effect being mediated by MCP–1 downregulation. Early stages of arteriosclerosis are associated... Show more…
Faculty
Faculté des sciences et de médecine
Department
Département de Médecine
Language
  • English
Classification
Medicine
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/299992