Life time—circadian clocks, mitochondria and metabolism
- Langmesser, Sonja Department of Medicine, Division of Biochemistry, University of Fribourg, Switzerland
- Albrecht, Urs Department of Medicine, Division of Biochemistry, University of Fribourg, Switzerland
-
2006
Published in:
- Chronobiology International. - 2006, vol. 23, no. 1-2, p. 51–157
oxidative phosphorylation
complex I
apoptosis
aging
neurodegenerative diseases
circadian clock
mitochondria
metabolism
English
A functional circadian clock has long been considered a selective advantage. Accumulating evidence shows that the clock coordinates a variety of physiological processes in order to schedule them to the optimal time of day and thus to synchronize metabolism to changes in external conditions. In mitochondria, both metabolic and cellular defense mechanisms are carefully regulated. Abnormal clock function, might influence mitochondrial function, resulting in decreased fitness of an organism.
- Faculty
- Faculté des sciences et de médecine
- Department
- Département de Biologie
- Language
-
- English
- Classification
- Medicine
- License
- License undefined
- Identifiers
-
- RERO DOC 5767
- DOI 10.1080/07420520500464437
- Persistent URL
- https://folia.unifr.ch/unifr/documents/299921
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