Characterization of renal interstitial fibroblast-specific protein 1/S100A4-positive cells in healthy and inflamed rodent kidneys
- Le Hir, Michel Anatomical Institute, Division of Vegetative Anatomy, University of Zurich, Switzerland
- Hegyi, Ivan Department of Pathology, Institut für Klinische Pathologie, University of Zürich, Switzerland
- Cueni-Loffing, Dominique Anatomical Institute, Division of Vegetative Anatomy, University of Zurich, Switzerland
- Loffing, Johannes Anatomy Unit, Medicine Department, University of Fribourg, Switzerland
- Kaissling, Brigitte Anatomical Institute, Division of Vegetative Anatomy, University of Zurich, Switzerland
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15.06.2005
Published in:
- Histochemistry and Cell Biology. - 2005, vol. 123(4-5), no. 335
kidney
fibroblast
myofibroblast
epithelial mesenchymal transition
thiazide
FSP1
S100A4
renal interstitium
English
Fibrosis is considered as a central factor in the loss of renal function in chronic kidney diseases. The origin of fibroblasts and myofibroblasts that accumulate in the interstitium of the diseased kidney is still a matter of debate. It has been shown that accumulation of myofibroblasts in inflamed and fibrotic kidneys is associated with upregulation of fibroblast-specific protein 1 (FSP1,... Show more…
- Faculty
- Faculté des sciences et de médecine
- Department
- Département de Médecine
- Language
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- English
- Classification
- Biology
- License
- License undefined
- Identifiers
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- RERO DOC 5139
- DOI 10.1007/s00418-005-0788-z
- Persistent URL
- https://folia.unifr.ch/unifr/documents/299898