Silencing dopamine D3-receptors in the nucleus accumbens shell in vivo induces changes in cocaine-induced hyperlocomotion
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Bahi, Amine
Biochemistry, Department of Medicine, Fribourg, Switzerland
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Boyer, Frederic
Biochemistry, Department of Medicine, Fribourg, Switzerland
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Bussard, Gaelle
Biochemistry, Department of Medicine, Fribourg, Switzerland
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Dreyer, Jean-Luc
Biochemistry, Department of Medicine, Fribourg, Switzerland
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Published in:
- European Journal of Neuroscience. - 2005, vol. 21(12), no. 3415
English
The dopamine D₃ receptor (D₃R) is an important pharmacotherapeutic target for its potential role in psychiatric disorders and drug dependence. To further explore its function in rats, a regulatable lentivirus, Lenti-D3, holding the rat D₃R cDNA, has been constructed as well as three nonregulatable lentiviruses, Lenti-D3-siRNA1, Lenti-D3-siRNA2 and Lenti-D3-siRNA3, expressing small hairpin... Show more…
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Faculty
- Faculté des sciences
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Department
- Médecine
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Language
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Classification
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Biology
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License
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License undefined
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Identifiers
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Persistent URL
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https://folia.unifr.ch/unifr/documents/299871