Journal article

Parvalbumin deficiency affects network properties resulting in increased susceptibility to epileptic seizures

  • Schwaller, Beat Division of Histology, Department of Medicine, University of Fribourg, Switzerland
  • Tetko, I. V. Laboratoire de Neuroheuristique, Institute of Physiology, University of Lausanne, Switzerland
  • Tandon, P. Department of Neurology, Children's Hospital and Harvard Medical School, Harvard Institute of Medicine, Boston, USA
  • Silveira, D. C. Department of Neurology, Children's Hospital and Harvard Medical School, Harvard Institute of Medicine, Boston, USA
  • Vreugdenhil, M. Division of Neuroscience, Department of Neurophysiology, Medical School, University of Birmingham, Edgbaston, Birmingham, UK
  • Henzi, Thomas Division of Histology, Department of Medicine, University of Fribourg, Switzerland
  • Potier, M. -C. Laboratoire de Neurobiologie, CNRS UMR7637, ESPCI, Paris, France
  • Celio, Marco R. Division of Histology, Department of Medicine, University of Fribourg, Switzerland
  • Villa, A. E. P. Laboratoire de Neuroheuristique, Institute of Physiology, University of Lausanne, Switzerland - Laboratoire de Neurobiophysique, INSERM U318, Université "Joseph Fourier", Grenoble, France
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    21.02.2004
Published in:
  • Molecular and Cellular Neuroscience. - 2004, vol. 25, no. 4, p. 650-663
English Networks of GABAergic interneurons are of utmost importance in generating and promoting synchronous activity and are involved in producing coherent oscillations. These neurons are characterized by their fast-spiking rate and by the expression of the Ca2+-binding protein parvalbumin (PV). Alteration of their inhibitory activity has been proposed as a major mechanism leading to epileptic... Show more…
Faculty
Faculté des sciences et de médecine
Department
Département de Médecine
Language
  • English
Classification
Biology
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/299739