Nitric oxide synthase gene transfer inhibits biological features of bypass graft disease in the human saphenous vein
- Tanner, Felix C. Cardiovascular Research, Clinic for Cardiovascular Surgery and Department of Clinical Research, University Hospital, Bern, Switzerland
- Largiadèr, Thomas Cardiovascular Research, Physiology Institute, University Zürich-Irchel and Division of Cardiology, University Hospital, Zürich, Switzerland
- Greutert, Helen Cardiovascular Research, Clinic for Cardiovascular Surgery and Department of Clinical Research, University Hospital, Bern, Switzerland
- Yang, Zhihong Physiology Institute, University of Fribourg, Fribourg, Switzerland
- Lüscher, Thomas F. Cardiovascular Research, Physiology Institute, University Zürich-Irchel and Division of Cardiology, University Hospital, Zürich, Switzerland
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28.01.2004
Published in:
- Journal of Thoracic and Cardiovascular Surgery. - 2004, vol. 127, no. 1, p. 20-26
English
Background Bypass graft disease is related to proliferation and migration of vascular smooth muscle cells and to platelet activation with thrombus formation. Nitric oxide inhibits these biological responses; it has never been demonstrated, however, whether this occurs in intact human vascular tissue after endothelial nitric oxide synthase gene transfer. Methods We examined whether endothelial... Show more…
- Faculty
- Faculté des sciences et de médecine
- Department
- Département de Médecine
- Language
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- English
- Classification
- Medicine
- License
- License undefined
- Identifiers
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- RERO DOC 4889
- DOI 10.1016/j.jtcvs.2003.07.021
- Persistent URL
- https://folia.unifr.ch/unifr/documents/299568