Journal article

Nitric oxide synthase gene transfer inhibits biological features of bypass graft disease in the human saphenous vein

  • Tanner, Felix C. Cardiovascular Research, Clinic for Cardiovascular Surgery and Department of Clinical Research, University Hospital, Bern, Switzerland
  • Largiadèr, Thomas Cardiovascular Research, Physiology Institute, University Zürich-Irchel and Division of Cardiology, University Hospital, Zürich, Switzerland
  • Greutert, Helen Cardiovascular Research, Clinic for Cardiovascular Surgery and Department of Clinical Research, University Hospital, Bern, Switzerland
  • Yang, Zhihong Physiology Institute, University of Fribourg, Fribourg, Switzerland
  • Lüscher, Thomas F. Cardiovascular Research, Physiology Institute, University Zürich-Irchel and Division of Cardiology, University Hospital, Zürich, Switzerland
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    28.01.2004
Published in:
  • Journal of Thoracic and Cardiovascular Surgery. - 2004, vol. 127, no. 1, p. 20-26
English Background Bypass graft disease is related to proliferation and migration of vascular smooth muscle cells and to platelet activation with thrombus formation. Nitric oxide inhibits these biological responses; it has never been demonstrated, however, whether this occurs in intact human vascular tissue after endothelial nitric oxide synthase gene transfer. Methods We examined whether endothelial... Show more…
Faculty
Faculté des sciences et de médecine
Department
Département de Médecine
Language
  • English
Classification
Medicine
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/299568