Bcl-2 family members: intracellular targeting, membrane-insertion, and changes in subcellular localization
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Schinzel, Anna
Institute for Molecular Medicine and Cell Research, Albert-Ludwigs-University Freiburg, Freiburg, Germany - Biochemistry Unit, Department of Medicine, Fribourg University, Switzerland
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Kaufmann, Thomas
Institute for Molecular Medicine and Cell Research, Albert-Ludwigs-University Freiburg, Freiburg, Germany - Biochemistry Unit, Department of Medicine, Fribourg University, Switzerland
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Borner, Christoph
Institute for Molecular Medicine and Cell Research, Albert-Ludwigs-University Freiburg, Freiburg, Germany
Published in:
- Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. - 2004, vol. 1644, no. 2, p. 95-105
English
The members of the Bcl-2 family of proteins are crucial regulators of apoptosis. In order to determine cell fate, these proteins must be targeted to distinct intracellular membranes, including the mitochondrial outer membrane (MOM), the membrane of the endoplasmic reticulum (ER) and its associated nuclear envelope. The targeting sequences and mechanisms that mediate the specificity of these... Show more…
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Faculty
- Faculté des sciences et de médecine
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Department
- Médecine
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Language
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Classification
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Biology
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License
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License undefined
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Identifiers
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Persistent URL
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https://folia.unifr.ch/unifr/documents/299543