The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research.
- Percie du Sert N NC3Rs, London, UK.
- Hurst V NC3Rs, London, UK.
- Ahluwalia A The William Harvey Research Institute, London, UK.
- Alam S Taylor & Francis Group, London, UK.
- Avey MT Health Science Practice, ICF, Durham, North Carolina, USA.
- Baker M Nature, San Francisco, California, USA.
- Browne WJ School of Education, University of Bristol, Bristol, UK.
- Clark A PLOS ONE, Cambridge, UK.
- Cuthill IC School of Biological Sciences, University of Bristol, Bristol, UK.
- Dirnagl U QUEST Center for Transforming Biomedical Research, Berlin Institute of Health & Department of Experimental Neurology, Charite Universitätsmedizin Berlin, Berlin, Germany.
- Emerson M National Heart and Lung Institute, Imperial College London, London, UK.
- Garner P Centre for Evidence Synthesis in Global Health, Clinical Sciences Department, Liverpool School of Tropical Medicine, Liverpool, UK.
- Holgate ST Clinical and Experimental Sciences, University of Southampton, Southampton, UK.
- Howells DW Tasmanian School of Medicine, University of Tasmania, Hobart, Australia.
- Karp NA Data Sciences & Quantitative Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge, UK.
- Lazic SE Prioris.ai Inc, Ottawa, Canada.
- Lidster K NC3Rs, London, UK.
- MacCallum CJ Hindawi Ltd, London, UK.
- Macleod M University of Edinburgh, Edinburgh, UK.
- Pearl EJ NC3Rs, London, UK.
- Petersen OH Academia Europaea Knowledge Hub, Cardiff University, Cardiff, UK.
- Rawle F Medical Research Council, London, UK.
- Reynolds P Statistics in Anesthesiology Research (STAR) Core & Research Assistant Professor, Department of Anesthesiology, College of Medicine, University of Florida, Gainesville, Florida, USA.
- Rooney K Discipline of Exercise and Sport Science, Faculty of Medicine and Health, University of Sydney, Sydney, Australia.
- Sena ES University of Edinburgh, Edinburgh, UK.
- Silberberg SD National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, USA.
- Steckler T Janssen Pharmaceutica NV, Beerse, Belgium.
- Würbel H Veterinary Public Health Institute, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
- 2020-07-15
Published in:
- British journal of pharmacology. - 2020
English
Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve the reporting of animal research. They consist of a checklist of information to include in publications describing in vivo experiments to enable others to scrutinise the work adequately, evaluate its methodological rigour, and reproduce the methods and results. Despite considerable levels of endorsement by funders and journals over the years, adherence to the guidelines has been inconsistent, and the anticipated improvements in the quality of reporting in animal research publications have not been achieved. Here, we introduce ARRIVE 2.0. The guidelines have been updated and information reorganised to facilitate their use in practice. We used a Delphi exercise to prioritise and divide the items of the guidelines into 2 sets, the "ARRIVE Essential 10," which constitutes the minimum requirement, and the "Recommended Set," which describes the research context. This division facilitates improved reporting of animal research by supporting a stepwise approach to implementation. This helps journal editors and reviewers verify that the most important items are being reported in manuscripts. We have also developed the accompanying Explanation and Elaboration (E&E) document, which serves (1) to explain the rationale behind each item in the guidelines, (2) to clarify key concepts, and (3) to provide illustrative examples. We aim, through these changes, to help ensure that researchers, reviewers, and journal editors are better equipped to improve the rigour and transparency of the scientific process and thus reproducibility.
- Language
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- English
- Open access status
- hybrid
- Identifiers
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- DOI 10.1111/bph.15193
- PMID 32662519
- Persistent URL
- https://folia.unifr.ch/global/documents/9770
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