Journal article
Efficacy of TachoSil a fibrin-based haemostat in different fields of surgery--a systematic review.
- Rickenbacher A University Hospital Zurich, Department of Visceral and Transplantation Surgery, Zurich, Switzerland.
- Breitenstein S
- Lesurtel M
- Frilling A
- 2009-06-17
Published in:
- Expert opinion on biological therapy. - 2009
Animals
Drug Combinations
Fibrinogen
Hemostasis
Humans
Intraoperative Complications
Surgical Procedures, Operative
Thrombin
English
BACKGROUND
Proper haemostasis is an important prerequisite for a successful outcome in all operative fields. TachoSil is used in many surgical specialties, especially for diffuse bleeding. However, TachoSil is not only used for haemostasis but also for closure of other anatomical structures.
OBJECTIVE
To review the literature concerning the efficacy of TachoSil, a topical fibrin-based haemostat.
METHODS
PubMed was searched for data on TachoSil and TachoComb from clinical trials and basic research.
RESULTS/CONCLUSION
TachoSil is used in many surgical specialties and has proven to be a valuable tool for several indications. It also seems to be cost effective. Solid data from randomized controlled trials are available for liver surgery, thoracic surgery and urology where a positive value is clearly documented.
Proper haemostasis is an important prerequisite for a successful outcome in all operative fields. TachoSil is used in many surgical specialties, especially for diffuse bleeding. However, TachoSil is not only used for haemostasis but also for closure of other anatomical structures.
OBJECTIVE
To review the literature concerning the efficacy of TachoSil, a topical fibrin-based haemostat.
METHODS
PubMed was searched for data on TachoSil and TachoComb from clinical trials and basic research.
RESULTS/CONCLUSION
TachoSil is used in many surgical specialties and has proven to be a valuable tool for several indications. It also seems to be cost effective. Solid data from randomized controlled trials are available for liver surgery, thoracic surgery and urology where a positive value is clearly documented.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1517/14712590903029172
- PMID 19527109
- Persistent URL
- https://folia.unifr.ch/global/documents/75190
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