OMA Browser--exploring orthologous relations across 352 complete genomes.
- Schneider A Institute of Computational Science, ETH Zurich, Switzerland. schneadr@inf.ethz.ch
- Dessimoz C
- Gonnet GH
- 2007-06-05
Published in:
- Bioinformatics (Oxford, England). - 2007
Base Pair Mismatch
Base Sequence
Chromosome Mapping
Computer Graphics
Conserved Sequence
Evolution, Molecular
Molecular Sequence Data
Sequence Alignment
Sequence Analysis, DNA
Sequence Homology, Nucleic Acid
Software
English
MOTIVATION
Inference of the evolutionary relation between proteins, in particular the identification of orthologs, is a central problem in comparative genomics. Several large-scale efforts with various methodologies and scope tackle this problem, including OMA (the Orthologous MAtrix project).
RESULTS
Based on the results of the OMA project, we introduce here the OMA Browser, a web-based tool allowing the exploration of orthologous relations over 352 complete genomes. Orthologs can be viewed as groups across species, but also at the level of sequence pairs, allowing the distinction among one-to-one, one-to-many and many-to-many orthologs.
AVAILABILITY
http://omabrowser.org.
Inference of the evolutionary relation between proteins, in particular the identification of orthologs, is a central problem in comparative genomics. Several large-scale efforts with various methodologies and scope tackle this problem, including OMA (the Orthologous MAtrix project).
RESULTS
Based on the results of the OMA project, we introduce here the OMA Browser, a web-based tool allowing the exploration of orthologous relations over 352 complete genomes. Orthologs can be viewed as groups across species, but also at the level of sequence pairs, allowing the distinction among one-to-one, one-to-many and many-to-many orthologs.
AVAILABILITY
http://omabrowser.org.
- Language
-
- English
- Open access status
- green
- Identifiers
-
- DOI 10.1093/bioinformatics/btm295
- PMID 17545180
- Persistent URL
- https://folia.unifr.ch/global/documents/67143
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