Journal article
Microcystic macular edema in optic nerve atrophy: a case series.
- Voide N Department of Ophthalmology, University of Lausanne, Jules Gonin Eye Hospital, Fondation Asile des Aveugles, Lausanne, Switzerland.
- Borruat FX Department of Ophthalmology, University of Lausanne, Jules Gonin Eye Hospital, Fondation Asile des Aveugles, Lausanne, Switzerland.
- 2015-04-23
Published in:
- Klinische Monatsblatter fur Augenheilkunde. - 2015
Adolescent
Adult
Aged
Aged, 80 and over
Angiography
Female
Humans
Macular Edema
Male
Middle Aged
Optic Atrophy
Reproducibility of Results
Sensitivity and Specificity
Tomography, Optical Coherence
Young Adult
English
BACKGROUND
Microcystic macular edema can occur after optic neuropathies of various etiologies, and is easily demonstrated by OCT. We report a cohort of patients with microcystic macular edema.
PATIENTS AND METHODS
All patients with optic neuropathy and microcystic macular edema were enrolled. Demographics, visual function, retinal angiographies and OCT parameters were studied.
RESULTS
Nineteen patients (23 eyes) exhibited microcystic macular edema: 10 men/9 women, aged 17-91 years. Etiologies of optic nerve atrophy were compressive (5), inflammatory (4), glaucoma (3), ischemic (3), trauma (2), degenerative (1), and hereditary (1). Median visual acuity was 4/10 (NLP-12/10). Fluorescein angiography showed no leakage. Topography of the microcystic macular edema correlated with near infrared images but with visual field defects in only 26%. OCT parameters were all abnormal.
CONCLUSIONS
Microcystic macular edema is a non-specific manifestation from an optic neuropathy of any etiology. The precise mechanism leading to microcystic macular edema remains unknown but trans-synaptic retrograde degeneration with Müller cells dysfunction is likely.
Microcystic macular edema can occur after optic neuropathies of various etiologies, and is easily demonstrated by OCT. We report a cohort of patients with microcystic macular edema.
PATIENTS AND METHODS
All patients with optic neuropathy and microcystic macular edema were enrolled. Demographics, visual function, retinal angiographies and OCT parameters were studied.
RESULTS
Nineteen patients (23 eyes) exhibited microcystic macular edema: 10 men/9 women, aged 17-91 years. Etiologies of optic nerve atrophy were compressive (5), inflammatory (4), glaucoma (3), ischemic (3), trauma (2), degenerative (1), and hereditary (1). Median visual acuity was 4/10 (NLP-12/10). Fluorescein angiography showed no leakage. Topography of the microcystic macular edema correlated with near infrared images but with visual field defects in only 26%. OCT parameters were all abnormal.
CONCLUSIONS
Microcystic macular edema is a non-specific manifestation from an optic neuropathy of any etiology. The precise mechanism leading to microcystic macular edema remains unknown but trans-synaptic retrograde degeneration with Müller cells dysfunction is likely.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1055/s-0035-1545797
- PMID 25902097
- Persistent URL
- https://folia.unifr.ch/global/documents/54970
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