Journal article
Tunable carbon nanotube/protein core-shell nanoparticles with NIR- and enzymatic-responsive cytotoxicity.
- Li C ETH Zurich, Department of Health Science & Technology, Schmelzbergstrasse 9, Zürich, Switzerland.
- Bolisetty S
- Chaitanya K
- Adamcik J
- Mezzenga R
- 2012-11-09
Published in:
- Advanced materials (Deerfield Beach, Fla.). - 2013
Cell Line, Tumor
Cell Survival
Humans
Hydrogen-Ion Concentration
Infrared Rays
Lactoglobulins
Nanoparticles
Nanotubes, Carbon
Proteins
Temperature
English
A unique procedure is developed to capture carbon nanotubes into closed virus-like protein cages with a controllable shell. The cross-linked shell varies in thickness within ≈10(0) -10(2) nm, and can be entirely removed by enzyme degradation. The cytotoxicity is entirely suppressed, but can be promoted again by enzymes and near-infrared light. These hybrids can be decorated with functional inorganic nanoparticles or processed into nanocomposites.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1002/adma.201203382
- PMID 23135812
- Persistent URL
- https://folia.unifr.ch/global/documents/54928
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