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Metal Compounds against Neglected Tropical Diseases.
Journal article

Metal Compounds against Neglected Tropical Diseases.

  • Ong YC Laboratory for Inorganic Chemical Biology, Chimie ParisTech , PSL University , 11 rue Pierre et Marie Curie , F-75005 Paris , France.
  • Roy S Department of Chemistry , University of Zurich , Wintherthurerstrasse 190 , CH-8057 Zurich , Switzerland.
  • Andrews PC School of Chemistry , Monash University , Wellington Road , Clayton , Victoria 3800 , Australia.
  • Gasser G Laboratory for Inorganic Chemical Biology, Chimie ParisTech , PSL University , 11 rue Pierre et Marie Curie , F-75005 Paris , France.
  • 2018-12-04
Published in:
  • Chemical reviews. - 2019
Bismuth
Coordination Complexes
Humans
Intercalating Agents
Metals
Neglected Diseases
Reactive Oxygen Species
English Many first-line treatments for neglected tropical diseases identified by the World Health Organization (WHO) are limited by one or more of the following: the development of drug resistance, toxicity, and side effects, lack of selectivity, narrow therapeutic indices, route of administration, and bioavailability. As such, there is an urgent need to develop viable alternatives to overcome these limitations. The following review provides an overview of all existing metal complexes studied and evaluates the status of these complexes on the respective disease of choice.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://folia.unifr.ch/global/documents/54226
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