Back
Quantitative analysis of benign paroxysmal positional vertigo fatigue under canalithiasis conditions.
Journal article

Quantitative analysis of benign paroxysmal positional vertigo fatigue under canalithiasis conditions.

  • Boselli F Institute of Fluid Dynamics, ETH Zurich, 8092 Zurich, Switzerland. Electronic address: boselli@ifd.mavt.ethz.ch.
  • Kleiser L Institute of Fluid Dynamics, ETH Zurich, 8092 Zurich, Switzerland. Electronic address: kleiser@ifd.mavt.ethz.ch.
  • Bockisch CJ Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich, 8092 Zurich, Switzerland; Department of Neurology, University Hospital Zurich, 8092 Zurich, Switzerland; Department of Ophthalmology, University Hospital Zurich, 8092 Zurich, Switzerland. Electronic address: Chris.Bockisch@usz.ch.
  • Hegemann SC Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich, 8092 Zurich, Switzerland. Electronic address: Stefan.Hegemann@usz.ch.
  • Obrist D Institute of Fluid Dynamics, ETH Zurich, 8092 Zurich, Switzerland. Electronic address: obrist@ifd.mavt.ethz.ch.
Show more…
  • 2014-04-12
Published in:
  • Journal of biomechanics. - 2014
BPPV
Canalithiasis
Endolymph flow
Force Coupling Method
Method of Fundamental Solutions
Nystagmus
Semicircular canals (SCCs)
Benign Paroxysmal Positional Vertigo
Computer Simulation
Eye Movements
Fatigue
Humans
Models, Anatomic
Nystagmus, Pathologic
Semicircular Canals
Time Factors
Vertigo
English In our daily life, small flows in the semicircular canals (SCCs) of the inner ear displace a sensory structure called the cupula which mediates the transduction of head angular velocities to afferent signals. We consider a dysfunction of the SCCs known as canalithiasis. Under this condition, small debris particles disturb the flow in the SCCs and can cause benign paroxysmal positional vertigo (BPPV), arguably the most common form of vertigo in humans. The diagnosis of BPPV is mainly based on the analysis of typical eye movements (positional nystagmus) following provocative head maneuvers that are known to lead to vertigo in BPPV patients. These eye movements are triggered by the vestibulo-ocular reflex, and their velocity provides an indirect measurement of the cupula displacement. An attenuation of the vertigo and the nystagmus is often observed when the provocative maneuver is repeated. This attenuation is known as BPPV fatigue. It was not quantitatively described so far, and the mechanisms causing it remain unknown. We quantify fatigue by eye velocity measurements and propose a fluid dynamic interpretation of our results based on a computational model for the fluid-particle dynamics of a SCC with canalithiasis. Our model suggests that the particles may not go back to their initial position after a first head maneuver such that a second head maneuver leads to different particle trajectories causing smaller cupula displacements.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://folia.unifr.ch/global/documents/52185
Statistics
Document views: 15 File downloads: