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T-Cell-Mediated Cross-Protective Immunity.
Journal article

T-Cell-Mediated Cross-Protective Immunity.

  • Khanna N Division of Infectious Diseases and Hospital Epidemiology, Departments of Biomedicine and Clinical Research, University Hospital of Basel, Basel, Switzerland.
  • Stuehler C Infection Biology Laboratory, Department of Biomedicine, University and University Hospital of Basel, Hebelstrasse 20, 4031, Basel, Switzerland. claudia.stuehler@unibas.ch.
  • 2017-06-07
Published in:
  • Methods in molecular biology (Clifton, N.J.). - 2017
Cross-reactive T cells
Dendritic cells
ELISpot
Heat-inactivated fungi
T cell clones
T cell lines
Antigen-Presenting Cells
Cell Line
Cross Reactions
Dendritic Cells
Enzyme-Linked Immunospot Assay
Epitopes, T-Lymphocyte
Fungal Vaccines
Fungi
Humans
Immunity, Cellular
T-Lymphocytes
Vaccines, Inactivated
English Human invasive fungal infections are caused by different mold and yeast species. Hence, cross-reactive T cells that recognize conserved epitopes of various fungal pathogens are of special interest for vaccination protocols or adoptive T cell transfer. Here, we describe an ELISpot-based method to test cross-reactivity of T cell lines or clones to different molds and yeasts.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://folia.unifr.ch/global/documents/49732
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