Second-hand smoke exposure in adulthood and lower respiratory health during 20 year follow up in the European Community Respiratory Health Survey.
- Flexeder C Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany. claudia.flexeder@helmholtz-muenchen.de.
- Zock JP Barcelona Institute for Global Health (ISGlobal), Barcelona, Spain.
- Jarvis D MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.
- Verlato G Unit of Epidemiology and Medical Statistics, Department of Diagnostics and Public Health, University of Verona, Verona, Italy.
- Olivieri M University Hospital of Verona, Verona, Italy.
- Benke G School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
- Abramson MJ School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
- Sigsgaard T Department of Public Health, Aarhus University, Aarhus, Denmark.
- Svanes C Centre for International Health, University of Bergen, Bergen, Norway.
- Torén K Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden.
- Nowak D Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital Munich (LMU), Munich, Germany.
- Jõgi R Lung Clinic, Tartu University Clinics, Tartu, Estonia.
- Martinez-Moratalla J Servicio de Neumología del Complejo, Servicio de Salud de Castilla - La Mancha (SESCAM), Hospitalario Universitario de Albacete, Albacete, Spain.
- Demoly P Department of Pulmonology, Division of Allergy, Hôpital Arnaud de Villeneuve, University Hospital of Montpellier, Montpellier, France.
- Janson C Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden.
- Gislason T Department of Sleep, Landspitali National University Hospital of Iceland, Reykjavik, Iceland.
- Bono R Department of Public Health and Pediatrics, University of Turin, Turin, Italy.
- Holm M Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden.
- Franklin KA Department of Surgical and Perioperative Sciences, Surgery, Umea University, Umea, Sweden.
- Garcia-Aymerich J Barcelona Institute for Global Health (ISGlobal), Barcelona, Spain.
- Siroux V Institute for Advanced Biosciences, UGA-Inserm U1209-CNRS UMR 5309, Joint Research Center, Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Site Santé - Allée des Alpes, 38700 La Tronche, Grenoble, France.
- Leynaert B Inserm, UMR 1152, Pathophysiology and Epidemiology of Respiratory Diseases, Paris, France, UMR 1152, University Paris Diderot Paris, Paris, France.
- Dorado Arenas S Pulmonology Department, Galdakao-Usansolo Hospital, Galdakao, Biscay, Spain.
- Corsico AG Division of Respiratory Diseases, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.
- Pereira-Vega A Respiratory and Allergy Clinical Unit, Universitary Hospitalary Complex, Huelva, Spain.
- Probst-Hensch N Swiss Tropical and Public Health Institute, Basel, Switzerland.
- Urrutia Landa I Pulmonary Department, Hospital Galdakao, Galdakao, Biscay, Spain.
- Schulz H Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.
- Heinrich J Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.
- 2019-02-16
Published in:
- Respiratory research. - 2019
Adults
Asthma
Bronchitis
ECRHS
Lung function
Respiratory symptoms
Smoking
Adult
Asthma
Bronchitis, Chronic
Dyspnea
Europe
European Union
Follow-Up Studies
Health Status
Health Surveys
Humans
Incidence
Prevalence
Respiratory Function Tests
Respiratory System
Respiratory Tract Diseases
Socioeconomic Factors
Tobacco Smoke Pollution
English
BACKGROUND
Early life exposure to tobacco smoke has been extensively studied but the role of second-hand smoke (SHS) for new-onset respiratory symptoms and lung function decline in adulthood has not been widely investigated in longitudinal studies. Our aim is to investigate the associations of exposure to SHS in adults with respiratory symptoms, respiratory conditions and lung function over 20 years.
METHODS
We used information from 3011 adults from 26 centres in 12 countries who participated in the European Community Respiratory Health Surveys I-III and were never or former smokers at all three surveys. Associations of SHS exposure with respiratory health (asthma symptom score, asthma, chronic bronchitis, COPD) were analysed using generalised linear mixed-effects models adjusted for confounding factors (including sex, age, smoking status, socioeconomic status and allergic sensitisation). Linear mixed-effects models with additional adjustment for height were used to assess the relationships between SHS exposure and lung function levels and decline.
RESULTS
Reported exposure to SHS decreased in all 26 study centres over time. The prevalence of SHS exposure was 38.7% at baseline (1990-1994) and 7.1% after the 20-year follow-up (2008-2011). On average 2.4% of the study participants were not exposed at the first, but were exposed at the third examination. An increase in SHS exposure over time was associated with doctor-diagnosed asthma (odds ratio (OR): 2.7; 95% confidence interval (95%-CI): 1.2-5.9), chronic bronchitis (OR: 4.8; 95%-CI: 1.6-15.0), asthma symptom score (count ratio (CR): 1.9; 95%-CI: 1.2-2.9) and dyspnoea (OR: 2.7; 95%-CI: 1.1-6.7) compared to never exposed to SHS. Associations between increase in SHS exposure and incidence of COPD (OR: 2.0; 95%-CI: 0.6-6.0) or lung function (β: - 49 ml; 95%-CI: -132, 35 for FEV1 and β: - 62 ml; 95%-CI: -165, 40 for FVC) were not apparent.
CONCLUSION
Exposure to second-hand smoke may lead to respiratory symptoms, but this is not accompanied by lung function changes.
Early life exposure to tobacco smoke has been extensively studied but the role of second-hand smoke (SHS) for new-onset respiratory symptoms and lung function decline in adulthood has not been widely investigated in longitudinal studies. Our aim is to investigate the associations of exposure to SHS in adults with respiratory symptoms, respiratory conditions and lung function over 20 years.
METHODS
We used information from 3011 adults from 26 centres in 12 countries who participated in the European Community Respiratory Health Surveys I-III and were never or former smokers at all three surveys. Associations of SHS exposure with respiratory health (asthma symptom score, asthma, chronic bronchitis, COPD) were analysed using generalised linear mixed-effects models adjusted for confounding factors (including sex, age, smoking status, socioeconomic status and allergic sensitisation). Linear mixed-effects models with additional adjustment for height were used to assess the relationships between SHS exposure and lung function levels and decline.
RESULTS
Reported exposure to SHS decreased in all 26 study centres over time. The prevalence of SHS exposure was 38.7% at baseline (1990-1994) and 7.1% after the 20-year follow-up (2008-2011). On average 2.4% of the study participants were not exposed at the first, but were exposed at the third examination. An increase in SHS exposure over time was associated with doctor-diagnosed asthma (odds ratio (OR): 2.7; 95% confidence interval (95%-CI): 1.2-5.9), chronic bronchitis (OR: 4.8; 95%-CI: 1.6-15.0), asthma symptom score (count ratio (CR): 1.9; 95%-CI: 1.2-2.9) and dyspnoea (OR: 2.7; 95%-CI: 1.1-6.7) compared to never exposed to SHS. Associations between increase in SHS exposure and incidence of COPD (OR: 2.0; 95%-CI: 0.6-6.0) or lung function (β: - 49 ml; 95%-CI: -132, 35 for FEV1 and β: - 62 ml; 95%-CI: -165, 40 for FVC) were not apparent.
CONCLUSION
Exposure to second-hand smoke may lead to respiratory symptoms, but this is not accompanied by lung function changes.
- Language
-
- English
- Open access status
- gold
- Identifiers
-
- DOI 10.1186/s12931-019-0996-z
- PMID 30764884
- Persistent URL
- https://folia.unifr.ch/global/documents/42116
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