Journal article
Carotid Intraplaque Neovascularization on Contrast-Enhanced Ultrasound Correlates with Cardiovascular Events and Poor Prognosis: A Systematic Review and Meta-analysis.
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Yan H
Department of Medical Ultrasound, West China Hospital, Sichuan University, Chengdu, China.
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Wu X
Department of Medical Ultrasound, West China Hospital, Sichuan University, Chengdu, China.
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He Y
Department of Medical Ultrasound, West China Hospital, Sichuan University, Chengdu, China.
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Staub D
Department of Angiology, University Hospital Basel, University of Basel, Basel, Switzerland.
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Wen X
Department of Medical Ultrasound, West China Hospital, Sichuan University, Chengdu, China.
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Luo Y
Department of Medical Ultrasound, West China Hospital, Sichuan University, Chengdu, China. Electronic address: luoyanddoc@163.com.
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Published in:
- Ultrasound in medicine & biology. - 2020
English
The goal of this meta-analysis is to investigate whether carotid intraplaque neovascularization (IPN) on contrast-enhanced ultrasound (CEUS) correlates with past cardiovascular events (CVEs) and prognosis. The present meta-analysis included 22 studies involving 3232 patients. The pooled analysis revealed that the presence of IPN was significantly associated with a higher incidence of future CVEs (pooled relative risk = 3.28, 95% confidence interval [CI]: 2.28-4.73) and a lower event-free probability (pooled hazard ratio = 2.51, 95% CI: 1.48-4.27). The presence of IPN was significantly associated with higher rates of past cardiac events (odds ratio = 4.25, 95% CI: 2.48-7.29) and past cerebrovascular accidents (odds ratio = 4.83, 95% CI: 2.66-8.78). Our results suggest that carotid IPN on CEUS significantly correlates with past cardiac events and cerebrovascular accidents and can predict future CVEs. Carotid CEUS is useful in CVE risk stratification.
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Language
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Open access status
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closed
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Persistent URL
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https://folia.unifr.ch/global/documents/40365
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