Journal article
Dual Photoredox/Nickel-Catalyzed Three-Component Carbofunctionalization of Alkenes.
- García-Domínguez A Department of Chemistry, University of Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
- Mondal R Department of Chemistry, University of Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
- Nevado C Department of Chemistry, University of Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
- 2019-06-27
Published in:
- Angewandte Chemie (International ed. in English). - 2019
English
The potential of merging photoredox and nickel catalysis to perform multicomponent alkene difunctionalizations under visible-light irradiation is demonstrated here. Secondary and tertiary alkyl groups, as well as sulfonyl moieties can be added to the terminal position of the double bond with simultaneous arylation of the internal carbon atom in a single step under mild reaction conditions. The process, devoid of stoichiometric additives, benefits from the use of bench-stable and easy-to-handle reagents, is operationally simple, and tolerates a wide variety of functional groups.
- Language
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- English
- Open access status
- closed
- Identifiers
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- DOI 10.1002/anie.201906692
- PMID 31242342
- Persistent URL
- https://folia.unifr.ch/global/documents/3693
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