Synthesis of a non-peptidic PET tracer designed for α5β1 integrin receptor
Université de Fribourg
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Monaco, Alessandra
Cyclotron Unit, University Hospital of Geneva, Switzerland - School of Pharmaceutical Sciences, University of Geneva and University of Lausanne, Switzerland
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Michelin, Olivier
Swiss Institute of Bioinformatics, University of Lausanne, Switzerland
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Prior, John
CHUV, Department of Nuclear Medicine, Lausanne, Switzerland
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Rüegg, Curzio
Faculty of Science, Department of Medicine, University of Fribourg, Switzerland
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Scapozza, Leonardo
School of Pharmaceutical Sciences, University of Geneva and University of Lausanne, Switzerland
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Seimbille, Yann
Cyclotron Unit, University Hospital of Geneva, Switzerland - School of Pharmaceutical Sciences, University of Geneva and University of Lausanne, Switzerland
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Published in:
- Journal of labelled compounds & radiopharmaceuticals. - 2014, vol. 57, no. 5, p. 365-370
English
Arginine–glycine–aspartic acid (RGD)-containing peptides have been traditionally used as PET probes to noninvasively image angiogenesis, but recently, small selective molecules for <em>α</em>₅<em>β</em>₁ integrin receptor have been developed with promising results. Sixty-one antagonists were screened, and <em>tert</em>-butyl (S)-3-(2-((3R,5S)-1-(3-(1-(2-fluoroethyl)-1H-1,2,3-triazol-4-... Show more…
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Faculty
- Faculté des sciences et de médecine
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Department
- Médecine 3ème année
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Language
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Classification
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Biology
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License
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License undefined
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Identifiers
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Persistent URL
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https://folia.unifr.ch/global/documents/303628