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Schistosoma mansoni venom allergen-like protein 4 (SmVAL4) is a novel lipid-binding SCP/TAPS protein that lacks the prototypical CAP motifs

Université de Fribourg

  • Kelleher, Allan National School of Tropical Medicine, Baylor College of Medicine, Houston, USA
  • Darwiche, Rabih Division of Biochemistry, Department ofBiology, University of Fribourg, Switzerland
  • Rezende, Wanderson C. National School of Tropical Medicine, Baylor College of Medicine, Houston, USA
  • Farias, Leonardo P. Centro de Biotecnologia, Instituto Butantan,São Paulo, Brazil
  • Leite, Luciana C. C. Centro de Biotecnologia, Instituto Butantan,São Paulo, Brazil
  • Schneiter, Roger Division of Biochemistry, Department ofBiology, University of Fribourg, Switzerland
  • Asojo, Oluwatoyin A. National School of Tropical Medicine, Baylor College of Medicine, Houston, USA
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    01.08.2014
Published in:
  • Acta Crystallographica Section D Biological Crystallography, 2014, vol. 70, no. 8, p. 2186–2196
English Schistosomiasis is a parasitic disease that affects over 200 million people. Vaccine candidates have been identified, including <i>Schistosoma mansoni</i> venom allergen- like proteins (SmVALs) from the SCP/TAPS (sperm-coating protein/Tpx/antigen 5/pathogenesis related-1/Sc7) superfamily. The first SmVAL structure, SmVAL4, was refined to a resolution limit of 2.16 Å. SmVAL4 has a unique... Show more…
Language
  • English
Identifiers
Classification
Biology
Faculty
Faculté des sciences
Department
Biologie
License
License undefined
Persistent URL
https://folia.unifr.ch/global/documents/303509
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Supplementary material
Supplementary material
Erratum: corrected fig. 6
Erratum: corrected fig. 6