pdf
pdf
Journal article

Weakening link to colorectal cancer ?

Université de Fribourg

  • Barbier, Maryse Institute of Biochemistry, University of Fribourg, Switzerland
  • Attoub, S. INSERM U482, Hôpital Saint-Antoine, Paris, France
  • Calvez, Ronan Institute of Biochemistry, University of Fribourg, Switzerland
  • Laffargue, Muriel Institute of Biochemistry, University of Fribourg, Switzerland
  • Jarry, A. INSERM U539, Hôtel-Dieu, Nantes, France
  • Mareel, M. Laboratory of Experimental Cancerology, Ghent University, Belgium
  • Altruda, F. Dipartimento di Genetica, Biologia e Biochimica, Università di Torino, Italy
  • Gespach, C. INSERM U482, Hôpital Saint-Antoine, Paris, France
  • Wu, D. Department of Genetics and Developmental Biology, University of Connecticut, Farmington, Connecticut, USA
  • Lu, B. Children's Hospital, Harvard Medical School, Boston, USA
  • Hirsch, E. Dipartimento di Genetica, Biologia e Biochimica, Università di Torino, Italy
  • Wymann, Matthias P. Institute of Biochemistry, University of Fribourg, Switzerland
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    2001
Published in:
  • Nature, 2001, vol. 413, p. 796
English The catalytic α-subunit of the enzyme phosphatidylinositol-3-OH kinase (PI(3)Kα) relays signals from G- protein-coupled receptors at the cell membrane and mediates leukocyte responses to chemokines and chemoattractants<sup>1, </sup><sup>2, </sup>³. Sasaki <i>et al</i>.⁴ report that mice that cannot produce PI(3)Kα have a high incidence of colorectal carcinomas, causing weight loss and... Show more…
Language
  • English
Identifiers
Classification
Medicine
Faculty
Faculté des sciences
Department
Médecine
License
License undefined
Persistent URL
https://folia.unifr.ch/global/documents/300274