The relationship between transportation noise exposure and ischemic heart disease: a meta-analysis.
- Vienneau D Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Socinstrasse 57, CH-4051 Basel, Switzerland; University of Basel, Basel, Switzerland. Electronic address: danielle.vienneau@unibas.ch.
- Schindler C Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Socinstrasse 57, CH-4051 Basel, Switzerland; University of Basel, Basel, Switzerland.
- Perez L Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Socinstrasse 57, CH-4051 Basel, Switzerland; University of Basel, Basel, Switzerland.
- Probst-Hensch N Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Socinstrasse 57, CH-4051 Basel, Switzerland; University of Basel, Basel, Switzerland.
- Röösli M Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Socinstrasse 57, CH-4051 Basel, Switzerland; University of Basel, Basel, Switzerland.
- 2015-03-14
Published in:
- Environmental research. - 2015
Exposure
Ischemic heart disease
Meta-analysis
Myocardial infarction
Transport noise
Environmental Exposure
Humans
Myocardial Ischemia
Noise, Transportation
Risk Assessment
English
BACKGROUND
There is a growing body of evidence that exposure to transportation related noise can adversely affect health and wellbeing. More recently, research on cardiovascular disease has specifically explored the hypothesis that exposure to transportation noise increases the risk for ischemic heart disease (IHD). Our objective was to review and conduct a meta-analysis to obtain an overall exposure-response association.
METHODS AND RESULTS
We conducted a systematic review and retained published studies on incident cases of IHD using sources of transportation noise as exposure. Study-specific results were transformed into risk estimates per 10dB increase in exposure. Subsequently we conducted a random effects meta-analysis to pool the estimates. We identified 10 studies on road and aircraft noise exposure conducted since the mid-1990s, providing a total of 12 risk estimates. Pooled relative risk for IHD was 1.06 (1.03-1.09) per 10dB increase in noise exposure with the linear exposure-response starting at 50dB. Based on a small number of studies, subgroup analyses were suggestive of higher risk for IHD for males compared to females (p=0.14), and for persons over 65 years of age compared to under (p=0.22). Air pollution adjustment, explored only in a subset of four studies, did not substantially attenuate the association between noise exposure and IHD.
CONCLUSIONS
The evidence for an effect of transportation noise with IHD necessitates further research into the threshold and the shape of the exposure-response association, potential sources of heterogeneity and effect modification. Research in different cultural contexts is also important to derive regional and local estimates for the contribution of transportation noise to the global burden of disease.
There is a growing body of evidence that exposure to transportation related noise can adversely affect health and wellbeing. More recently, research on cardiovascular disease has specifically explored the hypothesis that exposure to transportation noise increases the risk for ischemic heart disease (IHD). Our objective was to review and conduct a meta-analysis to obtain an overall exposure-response association.
METHODS AND RESULTS
We conducted a systematic review and retained published studies on incident cases of IHD using sources of transportation noise as exposure. Study-specific results were transformed into risk estimates per 10dB increase in exposure. Subsequently we conducted a random effects meta-analysis to pool the estimates. We identified 10 studies on road and aircraft noise exposure conducted since the mid-1990s, providing a total of 12 risk estimates. Pooled relative risk for IHD was 1.06 (1.03-1.09) per 10dB increase in noise exposure with the linear exposure-response starting at 50dB. Based on a small number of studies, subgroup analyses were suggestive of higher risk for IHD for males compared to females (p=0.14), and for persons over 65 years of age compared to under (p=0.22). Air pollution adjustment, explored only in a subset of four studies, did not substantially attenuate the association between noise exposure and IHD.
CONCLUSIONS
The evidence for an effect of transportation noise with IHD necessitates further research into the threshold and the shape of the exposure-response association, potential sources of heterogeneity and effect modification. Research in different cultural contexts is also important to derive regional and local estimates for the contribution of transportation noise to the global burden of disease.
- Language
-
- English
- Open access status
- green
- Identifiers
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- DOI 10.1016/j.envres.2015.02.023
- PMID 25769126
- Persistent URL
- https://folia.unifr.ch/global/documents/299018
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