Journal article
Primary ciliary dyskinesia with situs inversus totalis, hydrocephalus internus and cardiac malformations in a dog.
- Reichler IM Department of Reproduction, Faculty of Veterinary Medicine, University of Zurich, Switzerland.
- Hoerauf A
- Guscetti F
- Gardelle O
- Stoffel MH
- Jentsch B
- Walt H
- Arnold S
- 2001-08-02
Published in:
- The Journal of small animal practice. - 2001
Animals
Diagnosis, Differential
Dog Diseases
Dogs
Female
Hydrocephalus
Kartagener Syndrome
Radiography
Situs Inversus
Ultrasonography
English
A nine-month-old golden retriever bitch was presented with exercise intolerance and recurrent nasal discharge. Based on clinical, radiographic and ultrasonographic examination, a diagnosis of rhinitis, situs inversus totalis and tricuspid valve insufficiency was established. The results of video- and electron microscopy studies of the respiratory epithelium were compatible with primary ciliary dyskinesia (PCD). However, no evidence of a primary ultrastructural defect of the cilia was found. The dog was euthanased because of the poor prognosis. At necropsy, a hydrocephalus internus and a subaortic stenosis were additionally diagnosed. PCD, in combination with situs inversus, has been previously reported in golden retrievers, but without a concomitant hydrocephalus internus. Furthermore, concomitant occurrence of internal cardiac malformation and PCD has not previously been reported in the dog.
- Language
-
- English
- Open access status
- closed
- Identifiers
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- DOI 10.1111/j.1748-5827.2001.tb02471.x
- PMID 11480901
- Persistent URL
- https://folia.unifr.ch/global/documents/289576
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