Journal article
Fructose use in clinical nutrition: metabolic effects and potential consequences.
- Moulin S aDepartment of Critical Care Medicine, Hôpital cantonal de Fribourg, Fribourg bDepartment of Anaesthesia, Hôpital Riviera-Chablais, Montreux cDepartment of Physiology, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
- Seematter G
- Seyssel K
- 2017-04-07
Published in:
- Current opinion in clinical nutrition and metabolic care. - 2017
Animals
Brain
Fructose
Gastrointestinal Microbiome
Glucose Transporter Type 5
Humans
Intestinal Absorption
Mesentery
Metabolism
Nutrition Therapy
Parenteral Nutrition
Risk Factors
Second Messenger Systems
English
PURPOSE OF REVIEW
The current article presents recent findings on the metabolic effects of fructose.
RECENT FINDINGS
Fructose has always been considered as a simple 'caloric' hexose only metabolized by splanchnic tissues. Nevertheless, there is growing evidence that fructose acts as a second messenger and induces effects throughout the human body.
SUMMARY
Recent discoveries made possible with the evolution of technology have highlighted that fructose induces pleiotropic effects on different tissues. The fact that all these tissues express the specific fructose carrier GLUT5 let us reconsider that fructose is not only a caloric hexose, but could also be a potential actor of some behaviors and metabolic pathways. The physiological relevance of fructose as a metabolic driver is pertinent regarding recent scientific literature.
The current article presents recent findings on the metabolic effects of fructose.
RECENT FINDINGS
Fructose has always been considered as a simple 'caloric' hexose only metabolized by splanchnic tissues. Nevertheless, there is growing evidence that fructose acts as a second messenger and induces effects throughout the human body.
SUMMARY
Recent discoveries made possible with the evolution of technology have highlighted that fructose induces pleiotropic effects on different tissues. The fact that all these tissues express the specific fructose carrier GLUT5 let us reconsider that fructose is not only a caloric hexose, but could also be a potential actor of some behaviors and metabolic pathways. The physiological relevance of fructose as a metabolic driver is pertinent regarding recent scientific literature.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1097/MCO.0000000000000376
- PMID 28383298
- Persistent URL
- https://folia.unifr.ch/global/documents/27576
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