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Journal article

Noncoding RNAs in disease.

  • Lekka E Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zürich, Switzerland.
  • Hall J Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zürich, Switzerland.
  • 2018-07-05
Published in:
  • FEBS letters. - 2018
long noncoding RNA
microRNA
noncoding RNA
Cardiovascular Diseases
Gene Expression Regulation
Genetic Association Studies
Genetic Predisposition to Disease
Humans
Neoplasms
Nervous System Diseases
RNA, Long Noncoding
RNA, Untranslated
English Noncoding RNAs are emerging as potent and multifunctional regulators in all biological processes. In parallel, a rapidly growing number of studies has unravelled associations between aberrant noncoding RNA expression and human diseases. These associations have been extensively reviewed, often with the focus on a particular microRNA (miRNA) (family) or a selected disease/pathology. In this Mini-Review, we highlight a selection of studies in order to demonstrate the wide-scale involvement of miRNAs and long noncoding RNAs in the pathophysiology of three types of diseases: cancer, cardiovascular and neurological disorders. This research is opening new avenues to novel therapeutic approaches.
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  • English
Open access status
hybrid
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https://folia.unifr.ch/global/documents/275328
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