Journal article
A crystal structure of an oligoproline PPII-helix, at last.
- Wilhelm P Laboratory of Organic Chemistry, ETH Zurich , Vladimir-Prelog-Weg 3, CH-8093 Zurich, Switzerland.
- Lewandowski B
- Trapp N
- Wennemers H
- 2014-11-05
Published in:
- Journal of the American Chemical Society. - 2014
English
The first crystal structure of an oligoproline adopting an all-trans polyproline II (PPII) helix is presented. The high-resolution structure provides detailed insight into the dimensions and conformational properties of oligoprolines that are important for, e.g., their use as "molecular rulers" and "molecular scaffolds". The structure also showed that the amides interact with each other within a PPII helix and that water is not necessary for PPII helicity.
- Language
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- English
- Open access status
- closed
- Identifiers
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- DOI 10.1021/ja507405j
- PMID 25368901
- Persistent URL
- https://folia.unifr.ch/global/documents/275035
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