Viruses.STRING: A Virus-Host Protein-Protein Interaction Database.
- Cook HV Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, DK-2200 Copenhagen N, Danmark. helen.cook@gmail.com.
- Doncheva NT Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, DK-2200 Copenhagen N, Danmark. nadezhda.doncheva@cpr.ku.dk.
- Szklarczyk D Swiss Institute of Bioinformatics, University of Zurich, 8006 Zurich, Switzerland. damian.szklarczyk@imls.uzh.ch.
- von Mering C Swiss Institute of Bioinformatics, University of Zurich, 8006 Zurich, Switzerland. mering@imls.uzh.ch.
- Jensen LJ Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, DK-2200 Copenhagen N, Danmark. lars.juhl.jensen@cpr.ku.dk.
- 2018-09-26
Published in:
- Viruses. - 2018
PPI database
protein–protein interactions
virus bioinformatics
virus–host interactions
Animals
Databases, Protein
Gene Ontology
Host-Pathogen Interactions
Humans
Probability
Protein Binding
Protein Interaction Mapping
Protein Interaction Maps
Proteins
Software Design
Viruses
English
As viruses continue to pose risks to global health, having a better understanding of virus⁻host protein⁻protein interactions aids in the development of treatments and vaccines. Here, we introduce Viruses.STRING, a protein⁻protein interaction database specifically catering to virus⁻virus and virus⁻host interactions. This database combines evidence from experimental and text-mining channels to provide combined probabilities for interactions between viral and host proteins. The database contains 177,425 interactions between 239 viruses and 319 hosts. The database is publicly available at viruses.string-db.org, and the interaction data can also be accessed through the latest version of the Cytoscape STRING app.
- Language
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- English
- Open access status
- gold
- Identifiers
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- DOI 10.3390/v10100519
- PMID 30249048
- Persistent URL
- https://folia.unifr.ch/global/documents/266645
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