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[Acromegaly due to a pituitary tumor in a dog - diagnosis, therapy and long-term follow-up].
Journal article

[Acromegaly due to a pituitary tumor in a dog - diagnosis, therapy and long-term follow-up].

  • Reusch C Clinic for Small Animal Internal Medicine, Vetsuisse Faculty, University of Zurich.
  • Burkhardt WA Clinic for Small Animal Internal Medicine, Vetsuisse Faculty, University of Zurich.
  • Meier VS Division of Radiation Oncology, Vetsuisse Faculty, University of Zurich.
  • Rohrer Bley C Division of Radiation Oncology, Vetsuisse Faculty, University of Zurich.
  • Riond B Clinical Laboratory, Vetsuisse Faculty, University of Zurich.
  • Dennler M Clinic of Diagnostic Imaging, Vetsuisse Faculty, University of Zurich.
  • Boretti F Clinic for Small Animal Internal Medicine, Vetsuisse Faculty, University of Zurich.
  • Sieber-Ruckstuhl N Clinic for Small Animal Internal Medicine, Vetsuisse Faculty, University of Zurich.
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  • 2019-05-09
Published in:
  • Schweizer Archiv fur Tierheilkunde. - 2019
Acromegaly; pituitary tumor; diabetes mellitus; dog
Akromegalie; Hypophysentumor; Diabetes Mellitus; Hund
acromegalia; tumore pituitario; diabete mellito; cane
acromégalie; tumeur hypophysaire; diabète sucré; chien
Animals
Dog Diseases
Dogs
Growth Hormone
Growth Hormone-Secreting Pituitary Adenoma
Hormones
Insulin-Like Growth Factor I
Male
Radiotherapy
Somatostatin
Tomography, X-Ray Computed
Treatment Outcome
English Acromegaly due to a pituitary tumor has so far only been described in 3 dogs. The present case report describes a 7-year-old male-castrated Labrador Retriever which was referred because of difficult-to-control diabetes. Physical examination revealed markedly enlarged head, tongue and paws, widened interdental spaces and thickening of the skin in the head and neck area. IGF-1 and GH were increased and the latter continued to be abnormal after somatostatin application. Computed tomography demonstrated a space-occupying lesion in the pituitary gland and the diagnosis of acromegaly due to a GH-producing tumor of the pituitary was made. The dog underwent radiation therapy with a 6MV linear accelerator (3×8Gy) and improved substantially. Two and a half years after radiation therapy the dog developed lethargy and anorexia and was euthanized. Necropsy was not permitted. This case report represents the description of a dog suffering from pituitary-dependent acromegaly which was successfully treated and had a long-term survival.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://folia.unifr.ch/global/documents/259766
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