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A view of geriatrics through hormones. What is the relation between andropause and well-known geriatric syndromes?

  • Samaras N Department of Internal Medicine, Rehabilitation and Geriatrics, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil 4, 1205 Geneva, Switzerland. Electronic address: nikolassamaras@hotmail.com.
  • Samaras D Department of Medical Specialties, Clinical Nutrition, Geneva University Hospitals, Switzerland. Electronic address: Dimitrios.Samaras@hcuge.ch.
  • Lang PO Nescens Centre of Preventive Medicine, Clinic of Genolier, Genolier, Switzerland; Translational Medicine Research Group, Cranfield Health, Cranfield University, Cranfield, United Kingdom. Electronic address: polang@nescens.com.
  • Forster A Department of Internal Medicine, Rehabilitation and Geriatrics, Geneva University Hospitals, Switzerland. Electronic address: alexandre.forster@hcuge.ch.
  • Pichard C Department of Medical Specialties, Clinical Nutrition, Geneva University Hospitals, Switzerland. Electronic address: Claude.Pichard@hcuge.ch.
  • Frangos E Clinique de Jolimont, Geneva, Switzerland. Electronic address: Emilia.Frangos@hcuge.ch.
  • Meyer P Department of Medical Specialties, Endocrinology-Diabetology, Geneva University Hospitals, Switzerland. Electronic address: Patrick.Meyer@hcuge.ch.
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  • 2013-01-01
Published in:
  • Maturitas. - 2013
Andropause
Elderly
Geriatric syndromes
Testosterone
Aging
Andropause
Anemia
Cardiovascular Diseases
Cognition Disorders
Hormone Replacement Therapy
Humans
Life Style
Male
Mood Disorders
Osteoporosis
Testosterone
English Age related male hypogonadism, or "andropause", is increasingly recognized as of frequent occurrence in older patients. Diagnosis requires both the presence of clinical symptoms and low testosterone levels. However, diagnosing andropause in this age group may be challenging since symptoms are frequently non specific and testosterone levels are influenced by a multitude of parameters such as lifestyle factors and chronic diseases. In this article we discuss the pathophysiology, definition and diagnostic difficulties of andropause in geriatric patients. Moreover, we review the relation between testosterone levels and frequent geriatric syndromes such as falls, osteoporosis, cognitive and mood disorders, anemia and cardiovascular disease. Finally, we examine the potential benefits and risks of testosterone replacement therapy in this age group.
Language
  • English
Open access status
green
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Persistent URL
https://folia.unifr.ch/global/documents/254758
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