RE-CODE DCM (REsearch Objectives and Common Data Elements for Degenerative Cervical Myelopathy): A Consensus Process to Improve Research Efficiency in DCM, Through Establishment of a Standardized Dataset for Clinical Research and the Definition of the Research Priorities.
- Davies BM Academic Neurosurgery Unit, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
- Khan DZ Academic Neurosurgery Unit, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
- Mowforth OD Academic Neurosurgery Unit, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
- McNair AGK University of Bristol, Bristol, UK.
- Gronlund T James Lind Alliance, National Institute for Health Research, Southampton, UK.
- Kolias AG Academic Neurosurgery Unit, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
- Tetreault L Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.
- Starkey ML Academic Neurosurgery Unit, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
- Sadler I Myelopathy.org, Cambridge, UK.
- Sarewitz E Goffin Consultancy, Kent, UK.
- Houlton D Myelopathy.org, Cambridge, UK.
- Carter J Myelopathy.org, Cambridge, UK.
- Kalsi-Ryan S Toronto Rehabilitation Institute-LC, University Health Network, Toronto, Ontario, Canada.
- Aarabi B University of Maryland, Baltimore, MD, USA.
- Kwon BK Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
- Kurpad SN Medical College of Wisconsin, Milwaukee, WI, USA.
- Harrop J Thomas Jefferson University Hospital, Philadelphia, PA, USA.
- Wilson JR University of Toronto, Toronto, Ontario, Canada.
- Grossman R Houston Methodist Hospital, Houston, TX, USA.
- Curt A Balgrist University Hospital, Zurich, Switzerland.
- Fehlings MG Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.
- Kotter MRN Academic Neurosurgery Unit, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
- 2019-06-04
Published in:
- Global spine journal. - 2019
Core Outcomes in Effectiveness Trials (COMET)
Delphi
James Lind Alliance (JLA)
OPLL
audit
cervical
cervical stenosis
common data elements (CDE)
consensus
dataset
disc herniation
myelopathy
outcome
protocol
research priorities
spondylosis
surveillance
English
Study Design
Mixed-method consensus process.
Objectives
Degenerative cervical myelopathy (DCM) is a common and disabling condition that arises when mechanical stress damages the spinal cord as a result of degenerative changes in the surrounding spinal structures. RECODE-DCM (REsearch Objectives and Common Data Elements for Degenerative Cervical Myelopathy) aims to improve efficient use of health care resources within the field of DCM by using a multi-stakeholder partnership to define the DCM research priorities, to develop a minimum dataset for DCM clinical studies, and confirm a definition of DCM.
Methods
This requires a multi-stakeholder partnership and multiple parallel consensus development processes. It will be conducted via 4 phases, adhering to the guidance set out by the COMET (Core Outcomes in Effectiveness Trials) and JLA (James Lind Alliance) initiatives. Phase 1 will consist of preliminary work to inform online Delphi processes (Phase 2) and a consensus meeting (Phase 3). Following the findings of the consensus meeting, a synthesis of relevant measurement instruments will be compiled and assessed as per the COSMIN (Consensus-based Standards for the Selection of Health Measurement Instruments) criteria, to allow recommendations to be made on how to measure agreed data points. Phase 4 will monitor and promote the use of eventual recommendations.
Conclusions
RECODE-DCM sets out to establish for the first time an index term, minimum dataset, and research priorities together. Our aim is to reduce waste of health care resources in the future by using patient priorities to inform the scope of future DCM research activities. The consistent use of a standard dataset in DCM clinical studies, audit, and clinical surveillance will facilitate pooled analysis of future data and, ultimately, a deeper understanding of DCM.
Mixed-method consensus process.
Objectives
Degenerative cervical myelopathy (DCM) is a common and disabling condition that arises when mechanical stress damages the spinal cord as a result of degenerative changes in the surrounding spinal structures. RECODE-DCM (REsearch Objectives and Common Data Elements for Degenerative Cervical Myelopathy) aims to improve efficient use of health care resources within the field of DCM by using a multi-stakeholder partnership to define the DCM research priorities, to develop a minimum dataset for DCM clinical studies, and confirm a definition of DCM.
Methods
This requires a multi-stakeholder partnership and multiple parallel consensus development processes. It will be conducted via 4 phases, adhering to the guidance set out by the COMET (Core Outcomes in Effectiveness Trials) and JLA (James Lind Alliance) initiatives. Phase 1 will consist of preliminary work to inform online Delphi processes (Phase 2) and a consensus meeting (Phase 3). Following the findings of the consensus meeting, a synthesis of relevant measurement instruments will be compiled and assessed as per the COSMIN (Consensus-based Standards for the Selection of Health Measurement Instruments) criteria, to allow recommendations to be made on how to measure agreed data points. Phase 4 will monitor and promote the use of eventual recommendations.
Conclusions
RECODE-DCM sets out to establish for the first time an index term, minimum dataset, and research priorities together. Our aim is to reduce waste of health care resources in the future by using patient priorities to inform the scope of future DCM research activities. The consistent use of a standard dataset in DCM clinical studies, audit, and clinical surveillance will facilitate pooled analysis of future data and, ultimately, a deeper understanding of DCM.
- Language
-
- English
- Open access status
- gold
- Identifiers
-
- DOI 10.1177/2192568219832855
- PMID 31157148
- Persistent URL
- https://folia.unifr.ch/global/documents/235844
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