Journal article
Informative value of histological assessment of tissue acquired during aquablation of the prostate.
- Müllhaupt G Department of Urology, St. Gallen Cantonal Hospital, Klinik für Urologie, Rorschacherstrasse 95, 9007, St. Gallen, Switzerland. gautier.muellhaupt@kssg.ch.
- Enzler-Tschudy A Department of Pathology, St. Gallen Cantonal Hospital, St. Gallen, Switzerland.
- Horg K Department of Pathology, St. Gallen Cantonal Hospital, St. Gallen, Switzerland.
- Bubendorf L Institute of Medical Genetics and Pathology, University Hospital of Basel, Basel, Switzerland.
- Pratsinis M Department of Urology, St. Gallen Cantonal Hospital, Klinik für Urologie, Rorschacherstrasse 95, 9007, St. Gallen, Switzerland.
- Schmid HP Department of Urology, St. Gallen Cantonal Hospital, Klinik für Urologie, Rorschacherstrasse 95, 9007, St. Gallen, Switzerland.
- Abt D Department of Urology, St. Gallen Cantonal Hospital, Klinik für Urologie, Rorschacherstrasse 95, 9007, St. Gallen, Switzerland.
- 2020-09-09
Published in:
- World journal of urology. - 2020
English
PURPOSE
To determine the histological validity of the tissue acquired during aquablation of the prostate.
PATIENTS AND METHODS
Prostatic tissue of 12 patients that consecutively underwent aquablation for benign prostatic enlargement was systematically examined. Histological examination was performed by two experienced uropathologists using a digital slide scanner and slide viewer software (Pannoramic 250 and Case Viewer 2.3, 3D Histech, Hungary). The surface areas of the assessable glands were examined and set in relation to the total surface area of the material available for histology and to the patient's total prostate volume. Examinations were performed analogously in ten consecutive patients undergoing transurethral resection of the prostate (TURP) to facilitate interpretation of the results. Data were analyzed using descriptive statistics.
RESULTS
A median of 4.06% (range 1.43-7.5%) of the preoperative total prostate volume (median 64.5 ml (range 40-80 ml)) was obtained for histological examination by aquablation. Due to severe mechanical destruction and fragmentation, only a proportion of 0.43% (0.06-1.79%) of this tissue represented histologically assessable glands. Therefore, roughly 0.017% of the total prostatic volume was available for a reliable histological examination. In comparison, 32.5% (6.67-37.5%) of the total prostate volume was removed by TURP and 22.86% (7.45-40.57%) of this tissue represented informative prostatic glands, corresponding to 7.43% of the total prostate volume.
CONCLUSION
Histological significance of the tissue obtained by aquablation of the prostate is very limited. Costs and effort of the histological examination must, therefore, be weighed critically against the limited informative value.
To determine the histological validity of the tissue acquired during aquablation of the prostate.
PATIENTS AND METHODS
Prostatic tissue of 12 patients that consecutively underwent aquablation for benign prostatic enlargement was systematically examined. Histological examination was performed by two experienced uropathologists using a digital slide scanner and slide viewer software (Pannoramic 250 and Case Viewer 2.3, 3D Histech, Hungary). The surface areas of the assessable glands were examined and set in relation to the total surface area of the material available for histology and to the patient's total prostate volume. Examinations were performed analogously in ten consecutive patients undergoing transurethral resection of the prostate (TURP) to facilitate interpretation of the results. Data were analyzed using descriptive statistics.
RESULTS
A median of 4.06% (range 1.43-7.5%) of the preoperative total prostate volume (median 64.5 ml (range 40-80 ml)) was obtained for histological examination by aquablation. Due to severe mechanical destruction and fragmentation, only a proportion of 0.43% (0.06-1.79%) of this tissue represented histologically assessable glands. Therefore, roughly 0.017% of the total prostatic volume was available for a reliable histological examination. In comparison, 32.5% (6.67-37.5%) of the total prostate volume was removed by TURP and 22.86% (7.45-40.57%) of this tissue represented informative prostatic glands, corresponding to 7.43% of the total prostate volume.
CONCLUSION
Histological significance of the tissue obtained by aquablation of the prostate is very limited. Costs and effort of the histological examination must, therefore, be weighed critically against the limited informative value.
- Language
-
- English
- Open access status
- closed
- Identifiers
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- DOI 10.1007/s00345-020-03426-2
- PMID 32902728
- Persistent URL
- https://folia.unifr.ch/global/documents/232704
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