Journal article
Are avoidance diets still warranted in children with atopic dermatitis?
- Eigenmann PA Department of Woman, Child and Adolescent, Pediatric Allergy Unit, University Hospitals of Geneva, Geneva, Switzerland.
- Beyer K Department of Pediatric Pneumology, Immunology and Intensive Care, Charité Universitätsmedizin Berlin, Berlin, Germany.
- Lack G Department of Pediatric Allergy, Division of Asthma, Allergy and Lung Biology, King's College London and Guy's and St Thomas' National Health Service Foundation Trust, London, UK.
- Muraro A Department of Woman and Child Health, Food Allergy Centre, Padua University Hospital, Padua, Italy.
- Ong PY Keck School of Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA, USA.
- Sicherer SH Department of Pediatrics, Jaffe Food Allergy Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
- Sampson HA Department of Pediatrics, Jaffe Food Allergy Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
- 2019-07-06
Published in:
- Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology. - 2020
IgE testing
anaphylaxis
atopic dermatitis
avoidance diet
food allergy
oral tolerance induction
quality of life
English
Nearly 40% of children with moderate-to-severe atopic dermatitis (AD) have IgE-mediated food allergy (FA). This clinical observation has been extensively documented by experimental data linking skin inflammation in AD to FA, as well as by food challenges reproducing symptoms and avoidance diets improving AD. Although food avoidance may improve AD, avoidance diets do not cure AD, may even have detrimental effects such as progression to immediate-type allergy including anaphylactic reactions, and may significantly reduce the quality of life of the patient and the family. AD care should focus upon optimal medical management, rather than dietary elimination. Food allergy testing is primarily indicated when immediate-type allergic reactions are a concern. In recalcitrant AD, if food is being considered a possible chronic trigger, a limited panel of foods may be tested. An avoidance diet is only indicated in patients clearly identified as food allergic by an appropriate diagnostic food challenge, and after adequately informing the family of the limited benefits, and possible harms of an elimination diet.
- Language
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- English
- Open access status
- closed
- Identifiers
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- DOI 10.1111/pai.13104
- PMID 31273833
- Persistent URL
- https://folia.unifr.ch/global/documents/225072
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