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Peptide-MHC complexes assembled following multiple pathways: an opportunity for the design of vaccines and therapeutic molecules.
Journal article

Peptide-MHC complexes assembled following multiple pathways: an opportunity for the design of vaccines and therapeutic molecules.

  • Corradin G Institute of Biochemistry, University of Lausanne, Epalinges, Switzerland.
  • Demotz S
  • 1997-05-01
Published in:
  • Human immunology. - 1997
Antigen Presentation
Antigens
Epitopes
Histocompatibility Antigens Class I
Histocompatibility Antigens Class II
Humans
Major Histocompatibility Complex
Measles virus
Models, Immunological
Peptides
T-Lymphocytes
Vaccines
Viral Proteins
English Antigen degradation and peptide loading to major histocompatibility complex class I and class II molecules are described with special emphasis on "noncanonical" pathways. Examples of specific peptide loading for measles proteins are provided. In addition, characterization of defined epitopes presented to T cells can lead to the design of products of special interest in medicine and, in particular, in development of vaccines.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://folia.unifr.ch/global/documents/2125
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