Journal article
Methylpyrrole tropane alkaloids from the bark of Erythroxylum vacciniifolium.
- Zanolari B Laboratory of Pharmacognosy and Phytochemistry, University of Geneva, CH-1211 Geneva 4, Switzerland.
- Guilet D
- Marston A
- Queiroz EF
- Paulo Mde Q
- Hostettmann K
- 2005-08-30
Published in:
- Journal of natural products. - 2005
Alkaloids
Brazil
Bridged-Ring Compounds
Erythroxylaceae
Medicine, Traditional
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Plant Bark
Plants, Medicinal
Tropanes
English
Nine new tropane alkaloids substituted by a methylpyrrole moiety were isolated from the bark of Erythroxylum vacciniifolium, a Brazilian endemic plant used in traditional medicine and locally known as catuaba. All compounds were elucidated as tropanediol or -triol alkaloids esterified by at least one 1-methyl-1H-pyrrole-2-carboxylic acid. One of the isolated compounds was identified as a tropane alkaloid N-oxide. Their structures were determined by high-resolution mass spectrometry and multidimensional NMR spectroscopy.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1021/np040144h
- PMID 16124752
- Persistent URL
- https://folia.unifr.ch/global/documents/205559
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