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The life cycle of a transport vesicle.
Journal article

The life cycle of a transport vesicle.

  • Spang A Biozentrum, Growth and Development, University of Basel, Klingelbergstrasse 70, 4056 Basel, Switzerland. anne.spang@unibas.ch
  • 2008-08-30
Published in:
  • Cellular and molecular life sciences : CMLS. - 2008
ADP-Ribosylation Factors
Animals
Biological Transport
Cell Membrane
Coated Vesicles
Guanosine Triphosphate
Intracellular Membranes
SNARE Proteins
Transport Vesicles
Vesicular Transport Proteins
English Vesicular transport is the basic communication mechanism between different compartments in a cell and with the environment. In this review I discuss the principles of vesicle generation and consumption with particular emphasis on the different types of coat proteins and the timing of the shedding of the coat proteins from transport containers. In recent years it has become clear that there are more coat complexes than the classical COPI, COPII and clathrin coats. These additional coats may generate vesicles that transport cargo in a temporally and/or spatially controlled manner. Work over the last years suggests that GTP hydrolysis occurs early during vesicle biogenesis, destabilizing the coat perhaps before fission of the vesicle from the donor membrane occurs. Recent findings imply, however, that tethers at the receiving compartment specifically detect the coat on vesicle.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://folia.unifr.ch/global/documents/198601
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