Journal article
MARK-AGE biomarkers of ageing.
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Bürkle A
Molecular Toxicology Group, Department of Biology, Box 628, University of Konstanz, 78457 Konstanz, Germany. Electronic address: alexander.buerkle@uni-konstanz.de.
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Moreno-Villanueva M
Molecular Toxicology Group, Department of Biology, Box 628, University of Konstanz, 78457 Konstanz, Germany.
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Bernhard J
BioTeSys GmbH, 73728 Esslingen, Germany.
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Blasco M
Spanish National Cancer Research Centre (CNIO), 3 Melchor Fernandez Almagro, 28029 Madrid, Spain.
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Zondag G
DNage BV(1), Leiden, The Netherlands.
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Hoeijmakers JH
Department of Genetics, Erasmus University Medical Center, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands.
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Toussaint O
University of Namur, Research Unit on Cellular Biology, Rue de Bruxelles, 61, Namur B-5000, Belgium.
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Grubeck-Loebenstein B
Research Institute for Biomedical Aging Research, University of Innsbruck, Rennweg, 10, 6020 Innsbruck, Austria.
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Mocchegiani E
Translational Research Center of Nutrition and Ageing, IRCCS-INRCA, Via Birarelli 8, 60121 Ancona, Italy.
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Collino S
Nestlé Institute of Health Sciences SA, Molecular Biomarkers, EPFL Innovation Park, 1015 Lausanne, Switzerland.
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Gonos ES
National Hellenic Research Foundation, Institute of Biology, Medicinal Chemistry and Biotechnology, Athens, Greece.
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Sikora E
Laboratory of the Molecular Bases of Ageing, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur street, 02-093 Warsaw, Poland.
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Gradinaru D
Ana Aslan - National Institute of Gerontology and Geriatrics, Bucharest, Romania.
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Dollé M
National Institute for Public Health and the Environment (RIVM), Centre for Prevention and Health Services Research, P.O. Box 1, 3720 BA Bilthoven, The Netherlands.
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Salmon M
Straticell, Science Park Crealys, Rue Jean Sonet 10, 5032 Les Isnes, Belgium.
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Kristensen P
Department of Engineering - BCE Protein Engineering, Gustav Wiedsvej 10, 8000 Aarhus, Denmark.
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Griffiths HR
Life and Health Sciences, Aston Research Centre for Healthy Ageing, Aston University, Birmingham, UK.
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Libert C
Department for Molecular Biomedical Research, VIB, Ghent, Belgium.
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Grune T
Institute of Nutritional Medicine, University of Hohenheim, 70593 Stuttgart, Germany; Department of Nutritional Toxicology, Friedrich Schiller University Jena, Dornburger Str. 24, 07743 Jena, Germany.
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Breusing N
Institute of Nutritional Medicine, University of Hohenheim, 70593 Stuttgart, Germany.
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Simm A
Department of Cardiothoracic Surgery, University Hospital Halle, Ernst-Grube Str. 40, 06120 Halle (Saale), Germany.
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Franceschi C
CIG-Interdepartmental Center "L.Galvani", Alma Mater Studiorum, University of Bologna, 40126 Bologna, Italy.
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Capri M
CIG-Interdepartmental Center "L.Galvani", Alma Mater Studiorum, University of Bologna, 40126 Bologna, Italy.
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Talbot D
Unilever Corporate Research, Sharnbrook, UK.
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Caiafa P
Department of Cellular Biotechnologies and Hematology, Faculty of Pharmacy and Medicine, "Sapienza" University Rome, V.le Regina Elena 324, 00161 Rome, Italy.
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Friguet B
Sorbonne Universités, UPMC Univ Paris 06, UMR UPMC CNRS 8256, Biological adaptation and ageing - IBPS, INSERM U1164, F-75005 Paris, France.
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Slagboom PE
Department of Molecular Epidemiology, Leiden University Medical Centre, Leiden, The Netherlands.
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Hervonen A
Medical School, University of Tampere, 33014 Tampere, Finland.
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Hurme M
Medical School, University of Tampere, 33014 Tampere, Finland.
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Aspinall R
Regenerative Medicine Group, Cranfield Health, Cranfield, UK.
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Published in:
- Mechanisms of ageing and development. - 2015
English
Many candidate biomarkers of human ageing have been proposed in the scientific literature but in all cases their variability in cross-sectional studies is considerable, and therefore no single measurement has proven to serve a useful marker to determine, on its own, biological age. A plausible reason for this is the intrinsic multi-causal and multi-system nature of the ageing process. The recently completed MARK-AGE study was a large-scale integrated project supported by the European Commission. The major aim of this project was to conduct a population study comprising about 3200 subjects in order to identify a set of biomarkers of ageing which, as a combination of parameters with appropriate weighting, would measure biological age better than any marker in isolation.
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Language
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Open access status
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hybrid
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Identifiers
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Persistent URL
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https://folia.unifr.ch/global/documents/190457
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