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Changes in the epidemiological landscape of invasive candidiasis.
Journal article

Changes in the epidemiological landscape of invasive candidiasis.

  • Lamoth F Infectious Diseases Service, Department of Medicine, Lausanne University, Lausanne, Switzerland.
  • Lockhart SR Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA.
  • Berkow EL Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA.
  • Calandra T Infectious Diseases Service, Department of Medicine, Lausanne University, Lausanne, Switzerland.
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  • 2018-01-06
Published in:
  • The Journal of antimicrobial chemotherapy. - 2018
Antifungal Agents
Antimicrobial Stewardship
Candida
Candidiasis, Invasive
Drug Resistance, Fungal
Epidemiological Monitoring
Global Health
Humans
Prevalence
English The epidemiology of invasive candidiasis has evolved in recent years, warranting a review of the changes and the implications for current and future diagnosis and treatment. The overall burden of invasive candidiasis remains high, particularly in the expanding populations of patients at risk of opportunistic infection, such as the elderly or immunosuppressed. Progressive shifts from Candida albicans to non-albicans Candida spp. have been observed globally. The recent emergence of novel, multiresistant species, such as Candida auris, amplifies the call for vigilance in detection and advances in treatment. Among the current treatment options, fluconazole is still widely used throughout the world. Increased resistance to fluconazole, both acquired and naturally emerging, has been observed. Resistance to echinocandins is presently low but this may change with increased use. Improvement of diagnostic techniques and strategies, development of international surveillance networks and implementation of antifungal stewardship programmes represent major challenges for a better epidemiological control of invasive candidiasis.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://folia.unifr.ch/global/documents/182109
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