The effect of flammer-syndrome on retinal venous pressure.
- Fang L Department of Ophthalmology, University of Basel, Mittlere Strasse 91, 4031 Basel, Switzerland. Maneli.Mozaffarieh@usb.ch.
- Baertschi M
- Mozaffarieh M
- 2014-10-15
Published in:
- BMC ophthalmology. - 2014
Aged
Blood Pressure
Female
Glaucoma, Open-Angle
Humans
Intraocular Pressure
Male
Middle Aged
Ophthalmodynamometry
Peripheral Vascular Diseases
Retinal Vein
Tonometry, Ocular
Venous Pressure
English
BACKGROUND
The purpose of the study was to measure the retinal venous pressure (RVP) in the eyes of primary open-angle glaucoma (POAG) patients and healthy subjects with and without a Flammer-Syndrome (FS).
METHODS
RVP was measured in the following four groups of patients and age- and sex-matched healthy controls: (a) 15 patients with a POAG and a FS (POAG/FS+); (b) 15 patients with a POAG but without a FS (POAG/FS-); (c) 14 healthy subjects with a FS (healthy/FS+) and (d) 16 healthy subjects without a FS (healthy/FS-). RVP was measured in all participants bilaterally by means of contact lens ophthalmodynamometry. Ophthalmodynamometry is done by applying increasing pressure on the eye via a contact lens. The minimum force required to induce a venous pulsation is called ophthalmodynamometric force (ODF). The RVP is defined and calculated as the sum of ODF and intraocular pressure (IOP) [RVP = ODF + IOP].
RESULTS
The participants with a FS (whether patients with POAG or healthy subjects), had a significantly higher RVP compared to subjects without a FS (p = 0.0103). Patients with a POAG and FS (POAG/FS+) had a significantly higher RVP compared to patients without a FS (POAG/FS-) (p = 0.0301). There was a notable trend for a higher RVP in the healthy/FS + group compared to the healthy/FS - group, which did not reach statistical significance (p = 0.0898).
CONCLUSIONS
RVP is higher in subjects with a FS, particularly in glaucoma patients. The causal relationship needs to be further evaluated.
The purpose of the study was to measure the retinal venous pressure (RVP) in the eyes of primary open-angle glaucoma (POAG) patients and healthy subjects with and without a Flammer-Syndrome (FS).
METHODS
RVP was measured in the following four groups of patients and age- and sex-matched healthy controls: (a) 15 patients with a POAG and a FS (POAG/FS+); (b) 15 patients with a POAG but without a FS (POAG/FS-); (c) 14 healthy subjects with a FS (healthy/FS+) and (d) 16 healthy subjects without a FS (healthy/FS-). RVP was measured in all participants bilaterally by means of contact lens ophthalmodynamometry. Ophthalmodynamometry is done by applying increasing pressure on the eye via a contact lens. The minimum force required to induce a venous pulsation is called ophthalmodynamometric force (ODF). The RVP is defined and calculated as the sum of ODF and intraocular pressure (IOP) [RVP = ODF + IOP].
RESULTS
The participants with a FS (whether patients with POAG or healthy subjects), had a significantly higher RVP compared to subjects without a FS (p = 0.0103). Patients with a POAG and FS (POAG/FS+) had a significantly higher RVP compared to patients without a FS (POAG/FS-) (p = 0.0301). There was a notable trend for a higher RVP in the healthy/FS + group compared to the healthy/FS - group, which did not reach statistical significance (p = 0.0898).
CONCLUSIONS
RVP is higher in subjects with a FS, particularly in glaucoma patients. The causal relationship needs to be further evaluated.
- Language
-
- English
- Open access status
- gold
- Identifiers
-
- DOI 10.1186/1471-2415-14-121
- PMID 25312339
- Persistent URL
- https://folia.unifr.ch/global/documents/17982
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