Abatacept in the treatment of severe, longstanding, and refractory uveitis associated with juvenile idiopathic arthritis.

• Tappeiner C From the Department of Ophthalmology, Inselspital, University of Bern, Bern, Switzerland; Department of Ophthalmology, St. Franziskus Hospital, Münster, and University Duisburg-Essen, and Department of Ophthalmology, and Department of General Pediatrics, Centre for Pediatric and Adolescent Medicine, Interdisciplinary Uveitis Center, University of Heidelberg, Heidelberg, Germany; Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele, and Department of Rheumatology, Pediatric Rheumatology Unit, Istituto Ortopedico G. Pini University, Milan, Italy; Department of Ophthalmology, Hôpital Pitié-Salpêtrière, and Paris-Descartes University, IMAGINE and Pediatric Immunology-Hematology and Rheumatology Unit, Necker-Enfants Malades Hospital, Paris, France; Department of Ophthalmology, Helsinki University Hospital, Helsinki, Finland.C. Tappeiner, MD, Department of Ophthalmology, Inselspital, University of Bern, and Department of Ophthalmology, St. Franziskus Hospital, Münster; E. Miserocchi, MD, Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele; B. Bodaghi, MD, PhD, Department of Ophthalmology, Hôpital Pitié-Salpêtrière; K. Kotaniemi, MD, PhD, Department of Ophthalmology, Helsinki University Hospital; F. Mackensen, MD, Department of Ophthalmology and Interdisciplinary Uveitis Center, University of Heidelberg; V. Gerloni, MD, Department of Rheumatology, Pediatric Rheumatology Unit, Istituto Ortopedico G. Pini University;P. Quartier, MD, Paris-Descartes University, IMAGINE and Pediatric Immunology-Hematology and Rheumatology Unit, Necker-Enfants Malades Hospital; T. Lutz, MD, Department of General Pediatrics, Centre for Pediatric and Adolescent Medicine and Interdisciplinary Uveitis Center, University of Heidelberg; A. Heiligenhaus, MD, Department of Ophthalmology, St. Franziskus Hospital, Münster, and University Duisburg-Essen.
• Miserocchi E From the Department of Ophthalmology, Inselspital, University of Bern, Bern, Switzerland; Department of Ophthalmology, St. Franziskus Hospital, Münster, and University Duisburg-Essen, and Department of Ophthalmology, and Department of General Pediatrics, Centre for Pediatric and Adolescent Medicine, Interdisciplinary Uveitis Center, University of Heidelberg, Heidelberg, Germany; Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele, and Department of Rheumatology, Pediatric Rheumatology Unit, Istituto Ortopedico G. Pini University, Milan, Italy; Department of Ophthalmology, Hôpital Pitié-Salpêtrière, and Paris-Descartes University, IMAGINE and Pediatric Immunology-Hematology and Rheumatology Unit, Necker-Enfants Malades Hospital, Paris, France; Department of Ophthalmology, Helsinki University Hospital, Helsinki, Finland.C. Tappeiner, MD, Department of Ophthalmology, Inselspital, University of Bern, and Department of Ophthalmology, St. Franziskus Hospital, Münster; E. Miserocchi, MD, Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele; B. Bodaghi, MD, PhD, Department of Ophthalmology, Hôpital Pitié-Salpêtrière; K. Kotaniemi, MD, PhD, Department of Ophthalmology, Helsinki University Hospital; F. Mackensen, MD, Department of Ophthalmology and Interdisciplinary Uveitis Center, University of Heidelberg; V. Gerloni, MD, Department of Rheumatology, Pediatric Rheumatology Unit, Istituto Ortopedico G. Pini University;P. Quartier, MD, Paris-Descartes University, IMAGINE and Pediatric Immunology-Hematology and Rheumatology Unit, Necker-Enfants Malades Hospital; T. Lutz, MD, Department of General Pediatrics, Centre for Pediatric and Adolescent Medicine and Interdisciplinary Uveitis Center, University of Heidelberg; A. Heiligenhaus, MD, Department of Ophthalmology, St. Franziskus Hospital, Münster, and University Duisburg-Essen.
• Bodaghi B From the Department of Ophthalmology, Inselspital, University of Bern, Bern, Switzerland; Department of Ophthalmology, St. Franziskus Hospital, Münster, and University Duisburg-Essen, and Department of Ophthalmology, and Department of General Pediatrics, Centre for Pediatric and Adolescent Medicine, Interdisciplinary Uveitis Center, University of Heidelberg, Heidelberg, Germany; Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele, and Department of Rheumatology, Pediatric Rheumatology Unit, Istituto Ortopedico G. Pini University, Milan, Italy; Department of Ophthalmology, Hôpital Pitié-Salpêtrière, and Paris-Descartes University, IMAGINE and Pediatric Immunology-Hematology and Rheumatology Unit, Necker-Enfants Malades Hospital, Paris, France; Department of Ophthalmology, Helsinki University Hospital, Helsinki, Finland.C. Tappeiner, MD, Department of Ophthalmology, Inselspital, University of Bern, and Department of Ophthalmology, St. Franziskus Hospital, Münster; E. Miserocchi, MD, Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele; B. Bodaghi, MD, PhD, Department of Ophthalmology, Hôpital Pitié-Salpêtrière; K. Kotaniemi, MD, PhD, Department of Ophthalmology, Helsinki University Hospital; F. Mackensen, MD, Department of Ophthalmology and Interdisciplinary Uveitis Center, University of Heidelberg; V. Gerloni, MD, Department of Rheumatology, Pediatric Rheumatology Unit, Istituto Ortopedico G. Pini University;P. Quartier, MD, Paris-Descartes University, IMAGINE and Pediatric Immunology-Hematology and Rheumatology Unit, Necker-Enfants Malades Hospital; T. Lutz, MD, Department of General Pediatrics, Centre for Pediatric and Adolescent Medicine and Interdisciplinary Uveitis Center, University of Heidelberg; A. Heiligenhaus, MD, Department of Ophthalmology, St. Franziskus Hospital, Münster, and University Duisburg-Essen.
• Kotaniemi K From the Department of Ophthalmology, Inselspital, University of Bern, Bern, Switzerland; Department of Ophthalmology, St. Franziskus Hospital, Münster, and University Duisburg-Essen, and Department of Ophthalmology, and Department of General Pediatrics, Centre for Pediatric and Adolescent Medicine, Interdisciplinary Uveitis Center, University of Heidelberg, Heidelberg, Germany; Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele, and Department of Rheumatology, Pediatric Rheumatology Unit, Istituto Ortopedico G. Pini University, Milan, Italy; Department of Ophthalmology, Hôpital Pitié-Salpêtrière, and Paris-Descartes University, IMAGINE and Pediatric Immunology-Hematology and Rheumatology Unit, Necker-Enfants Malades Hospital, Paris, France; Department of Ophthalmology, Helsinki University Hospital, Helsinki, Finland.C. Tappeiner, MD, Department of Ophthalmology, Inselspital, University of Bern, and Department of Ophthalmology, St. Franziskus Hospital, Münster; E. Miserocchi, MD, Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele; B. Bodaghi, MD, PhD, Department of Ophthalmology, Hôpital Pitié-Salpêtrière; K. Kotaniemi, MD, PhD, Department of Ophthalmology, Helsinki University Hospital; F. Mackensen, MD, Department of Ophthalmology and Interdisciplinary Uveitis Center, University of Heidelberg; V. Gerloni, MD, Department of Rheumatology, Pediatric Rheumatology Unit, Istituto Ortopedico G. Pini University;P. Quartier, MD, Paris-Descartes University, IMAGINE and Pediatric Immunology-Hematology and Rheumatology Unit, Necker-Enfants Malades Hospital; T. Lutz, MD, Department of General Pediatrics, Centre for Pediatric and Adolescent Medicine and Interdisciplinary Uveitis Center, University of Heidelberg; A. Heiligenhaus, MD, Department of Ophthalmology, St. Franziskus Hospital, Münster, and University Duisburg-Essen.
• Mackensen F From the Department of Ophthalmology, Inselspital, University of Bern, Bern, Switzerland; Department of Ophthalmology, St. Franziskus Hospital, Münster, and University Duisburg-Essen, and Department of Ophthalmology, and Department of General Pediatrics, Centre for Pediatric and Adolescent Medicine, Interdisciplinary Uveitis Center, University of Heidelberg, Heidelberg, Germany; Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele, and Department of Rheumatology, Pediatric Rheumatology Unit, Istituto Ortopedico G. Pini University, Milan, Italy; Department of Ophthalmology, Hôpital Pitié-Salpêtrière, and Paris-Descartes University, IMAGINE and Pediatric Immunology-Hematology and Rheumatology Unit, Necker-Enfants Malades Hospital, Paris, France; Department of Ophthalmology, Helsinki University Hospital, Helsinki, Finland.C. Tappeiner, MD, Department of Ophthalmology, Inselspital, University of Bern, and Department of Ophthalmology, St. Franziskus Hospital, Münster; E. Miserocchi, MD, Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele; B. Bodaghi, MD, PhD, Department of Ophthalmology, Hôpital Pitié-Salpêtrière; K. Kotaniemi, MD, PhD, Department of Ophthalmology, Helsinki University Hospital; F. Mackensen, MD, Department of Ophthalmology and Interdisciplinary Uveitis Center, University of Heidelberg; V. Gerloni, MD, Department of Rheumatology, Pediatric Rheumatology Unit, Istituto Ortopedico G. Pini University;P. Quartier, MD, Paris-Descartes University, IMAGINE and Pediatric Immunology-Hematology and Rheumatology Unit, Necker-Enfants Malades Hospital; T. Lutz, MD, Department of General Pediatrics, Centre for Pediatric and Adolescent Medicine and Interdisciplinary Uveitis Center, University of Heidelberg; A. Heiligenhaus, MD, Department of Ophthalmology, St. Franziskus Hospital, Münster, and University Duisburg-Essen.
• Gerloni V From the Department of Ophthalmology, Inselspital, University of Bern, Bern, Switzerland; Department of Ophthalmology, St. Franziskus Hospital, Münster, and University Duisburg-Essen, and Department of Ophthalmology, and Department of General Pediatrics, Centre for Pediatric and Adolescent Medicine, Interdisciplinary Uveitis Center, University of Heidelberg, Heidelberg, Germany; Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele, and Department of Rheumatology, Pediatric Rheumatology Unit, Istituto Ortopedico G. Pini University, Milan, Italy; Department of Ophthalmology, Hôpital Pitié-Salpêtrière, and Paris-Descartes University, IMAGINE and Pediatric Immunology-Hematology and Rheumatology Unit, Necker-Enfants Malades Hospital, Paris, France; Department of Ophthalmology, Helsinki University Hospital, Helsinki, Finland.C. Tappeiner, MD, Department of Ophthalmology, Inselspital, University of Bern, and Department of Ophthalmology, St. Franziskus Hospital, Münster; E. Miserocchi, MD, Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele; B. Bodaghi, MD, PhD, Department of Ophthalmology, Hôpital Pitié-Salpêtrière; K. Kotaniemi, MD, PhD, Department of Ophthalmology, Helsinki University Hospital; F. Mackensen, MD, Department of Ophthalmology and Interdisciplinary Uveitis Center, University of Heidelberg; V. Gerloni, MD, Department of Rheumatology, Pediatric Rheumatology Unit, Istituto Ortopedico G. Pini University;P. Quartier, MD, Paris-Descartes University, IMAGINE and Pediatric Immunology-Hematology and Rheumatology Unit, Necker-Enfants Malades Hospital; T. Lutz, MD, Department of General Pediatrics, Centre for Pediatric and Adolescent Medicine and Interdisciplinary Uveitis Center, University of Heidelberg; A. Heiligenhaus, MD, Department of Ophthalmology, St. Franziskus Hospital, Münster, and University Duisburg-Essen.
• Quartier P From the Department of Ophthalmology, Inselspital, University of Bern, Bern, Switzerland; Department of Ophthalmology, St. Franziskus Hospital, Münster, and University Duisburg-Essen, and Department of Ophthalmology, and Department of General Pediatrics, Centre for Pediatric and Adolescent Medicine, Interdisciplinary Uveitis Center, University of Heidelberg, Heidelberg, Germany; Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele, and Department of Rheumatology, Pediatric Rheumatology Unit, Istituto Ortopedico G. Pini University, Milan, Italy; Department of Ophthalmology, Hôpital Pitié-Salpêtrière, and Paris-Descartes University, IMAGINE and Pediatric Immunology-Hematology and Rheumatology Unit, Necker-Enfants Malades Hospital, Paris, France; Department of Ophthalmology, Helsinki University Hospital, Helsinki, Finland.C. Tappeiner, MD, Department of Ophthalmology, Inselspital, University of Bern, and Department of Ophthalmology, St. Franziskus Hospital, Münster; E. Miserocchi, MD, Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele; B. Bodaghi, MD, PhD, Department of Ophthalmology, Hôpital Pitié-Salpêtrière; K. Kotaniemi, MD, PhD, Department of Ophthalmology, Helsinki University Hospital; F. Mackensen, MD, Department of Ophthalmology and Interdisciplinary Uveitis Center, University of Heidelberg; V. Gerloni, MD, Department of Rheumatology, Pediatric Rheumatology Unit, Istituto Ortopedico G. Pini University;P. Quartier, MD, Paris-Descartes University, IMAGINE and Pediatric Immunology-Hematology and Rheumatology Unit, Necker-Enfants Malades Hospital; T. Lutz, MD, Department of General Pediatrics, Centre for Pediatric and Adolescent Medicine and Interdisciplinary Uveitis Center, University of Heidelberg; A. Heiligenhaus, MD, Department of Ophthalmology, St. Franziskus Hospital, Münster, and University Duisburg-Essen.
• Lutz T From the Department of Ophthalmology, Inselspital, University of Bern, Bern, Switzerland; Department of Ophthalmology, St. Franziskus Hospital, Münster, and University Duisburg-Essen, and Department of Ophthalmology, and Department of General Pediatrics, Centre for Pediatric and Adolescent Medicine, Interdisciplinary Uveitis Center, University of Heidelberg, Heidelberg, Germany; Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele, and Department of Rheumatology, Pediatric Rheumatology Unit, Istituto Ortopedico G. Pini University, Milan, Italy; Department of Ophthalmology, Hôpital Pitié-Salpêtrière, and Paris-Descartes University, IMAGINE and Pediatric Immunology-Hematology and Rheumatology Unit, Necker-Enfants Malades Hospital, Paris, France; Department of Ophthalmology, Helsinki University Hospital, Helsinki, Finland.C. Tappeiner, MD, Department of Ophthalmology, Inselspital, University of Bern, and Department of Ophthalmology, St. Franziskus Hospital, Münster; E. Miserocchi, MD, Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele; B. Bodaghi, MD, PhD, Department of Ophthalmology, Hôpital Pitié-Salpêtrière; K. Kotaniemi, MD, PhD, Department of Ophthalmology, Helsinki University Hospital; F. Mackensen, MD, Department of Ophthalmology and Interdisciplinary Uveitis Center, University of Heidelberg; V. Gerloni, MD, Department of Rheumatology, Pediatric Rheumatology Unit, Istituto Ortopedico G. Pini University;P. Quartier, MD, Paris-Descartes University, IMAGINE and Pediatric Immunology-Hematology and Rheumatology Unit, Necker-Enfants Malades Hospital; T. Lutz, MD, Department of General Pediatrics, Centre for Pediatric and Adolescent Medicine and Interdisciplinary Uveitis Center, University of Heidelberg; A. Heiligenhaus, MD, Department of Ophthalmology, St. Franziskus Hospital, Münster, and University Duisburg-Essen.
• Heiligenhaus A From the Department of Ophthalmology, Inselspital, University of Bern, Bern, Switzerland; Department of Ophthalmology, St. Franziskus Hospital, Münster, and University Duisburg-Essen, and Department of Ophthalmology, and Department of General Pediatrics, Centre for Pediatric and Adolescent Medicine, Interdisciplinary Uveitis Center, University of Heidelberg, Heidelberg, Germany; Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele, and Department of Rheumatology, Pediatric Rheumatology Unit, Istituto Ortopedico G. Pini University, Milan, Italy; Department of Ophthalmology, Hôpital Pitié-Salpêtrière, and Paris-Descartes University, IMAGINE and Pediatric Immunology-Hematology and Rheumatology Unit, Necker-Enfants Malades Hospital, Paris, France; Department of Ophthalmology, Helsinki University Hospital, Helsinki, Finland.C. Tappeiner, MD, Department of Ophthalmology, Inselspital, University of Bern, and Department of Ophthalmology, St. Franziskus Hospital, Münster; E. Miserocchi, MD, Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele; B. Bodaghi, MD, PhD, Department of Ophthalmology, Hôpital Pitié-Salpêtrière; K. Kotaniemi, MD, PhD, Department of Ophthalmology, Helsinki University Hospital; F. Mackensen, MD, Department of Ophthalmology and Interdisciplinary Uveitis Center, University of Heidelberg; V. Gerloni, MD, Department of Rheumatology, Pediatric Rheumatology Unit, Istituto Ortopedico G. Pini University;P. Quartier, MD, Paris-Descartes University, IMAGINE and Pediatric Immunology-Hematology and Rheumatology Unit, Necker-Enfants Malades Hospital; T. Lutz, MD, Department of General Pediatrics, Centre for Pediatric and Adolescent Medicine and Interdisciplinary Uveitis Center, University of Heidelberg; A. Heiligenhaus, MD, Department of Ophthalmology, St. Franziskus Hospital, Münster, and University Duisburg-Essen. arnd.heiligenhaus@uveitis-zentrum.de.

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ABATACEPT

BIOLOGICALS

JUVENILE IDIOPATHIC ARTHRITIS

UVEITIS

Abatacept

Adolescent

Arthritis, Juvenile

Child

Female

Humans

Immunosuppressive Agents

Male

Retrospective Studies

Treatment Outcome

Uveitis