Journal article
Brain involvement in haemolytic-uraemic syndrome: MRI features of coagulative necrosis.
- Schmidt S Department of Diagnostic and Interventional Radiology, University Hospital-CHUV, Lausanne, Switzerland. sabschmidt67@hotmail.com
- Gudinchet F
- Meagher-Villemure K
- Maeder P
- 2001-08-22
Published in:
- Neuroradiology. - 2001
Blood Coagulation Disorders
Brain
Child, Preschool
Female
Hemolytic-Uremic Syndrome
Humans
Infant
Intracranial Thrombosis
Magnetic Resonance Imaging
Male
Necrosis
Radiography
English
We describe radiological demonstration of brain involvement in haemolytic-uraemic syndrome (HUS) in two siblings with a very different clinical course. While the brother presented with a mild, reversible encephalopathy, his sister developed high-signal lesions in the cortex, putamen and caudate nucleus on T1-weighted images, seen as dense areas on CT. Biopsy revealed coagulative necrosis due to microthrombosis without haemorrhage, calcification or infection. These findings suggest a possible prognostic role for MRI in cases of encephalopathy due to HUS.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1007/s002340100557
- PMID 11512592
- Persistent URL
- https://folia.unifr.ch/global/documents/137288
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