Management of Paediatric Ulcerative Colitis, Part 2: Acute Severe Colitis-An Evidence-based Consensus Guideline From the European Crohn's and Colitis Organization and the European Society of Paediatric Gastroenterology, Hepatology and Nutrition.
- Turner D Shaare Zedek Medical Center, The Hebrew University of Jerusalem, Jerusalem, Israel.
- Ruemmele FM Université Paris Descartes, Sorbonne Paris Cité, APHP, Hôpital Necker Enfants Malades, Paris, France.
- Orlanski-Meyer E Shaare Zedek Medical Center, The Hebrew University of Jerusalem, Jerusalem, Israel.
- Griffiths AM The Hospital for Sick Children, University of Toronto, Toronto, Canada.
- de Carpi JM Hospital Sant Joan de Déu, Barcelona, Spain.
- Bronsky J Department of Paediatrics, University Hospital Motol, Prague, Czech Republic.
- Veres G Ist Department of Pediatrics, Semmelweis University, Budapest, Hungary.
- Aloi M Pediatric Gastroenterology and Liver Unit, Sapienza University of Rome, Rome.
- Strisciuglio C Department of Woman, Child and General and Specialistic Surgery, University of Campania "Luigi Vanvitelli," Napoli, Italy.
- Braegger CP University Children's Hospital, Zurich, Switzerland.
- Assa A Schneider Children's Hospital, Petach Tikva (affiliated to the Sackler Faculty of Medicine), Tel Aviv University, Tel Aviv, Israel.
- Romano C Pediatric Department, University of Messina, Messina, Italy.
- Hussey S National Children's Research Centre, Royal College of Surgeons of Ireland and University College Dublin, Ireland.
- Stanton M Southampton Children's Hospital, Southampton, UK.
- Pakarinen M Helsinki University Children's Hospital, Department of Pediatric Surgery, Helsinki, Finland.
- de Ridder L Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands.
- Katsanos KH Medical School and University Hospital of Ioannina, Ioannina, Greece.
- Croft N Barts and the London School of Medicine, Queen Mary University of London, London, UK.
- Navas-López VM Pediatric Gastroenterology and Nutrition Unit, Hospital Materno, IBIMA, Málaga, Spain.
- Wilson DC Child Life and Health, University of Edinburgh, Edinburgh, UK.
- Lawrence S BC Children's Hospital, University of British Columbia, Vancouver BC, Canada.
- Russell RK The Royal Hospital for Children, Glasgow, UK.
- 2018-07-26
Published in:
- Journal of pediatric gastroenterology and nutrition. - 2018
Child
Child Nutritional Physiological Phenomena
Colitis, Ulcerative
Europe
Female
Humans
Male
Severity of Illness Index
Societies, Medical
English
BACKGROUND AND AIM
Acute severe colitis (ASC) is one of the few emergencies in pediatric gastroenterology. Tight monitoring and timely medical and surgical interventions may improve outcomes and minimize morbidity and mortality. We aimed to standardize daily treatment of ASC in children through detailed recommendations and practice points which are based on a systematic review of the literature and consensus of experts.
METHODS
These guidelines are a joint effort of the European Crohn's and Colitis Organization (ECCO) and the European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN). Fifteen predefined questions were addressed by working subgroups. An iterative consensus process, including 2 face-to-face meetings, was followed by voting of the national representatives of ECCO and all members of the Paediatric Inflammatory Bowel Disease (IBD) Porto group of ESPGHAN (43 voting experts).
RESULTS
A total of 24 recommendations and 43 practice points were endorsed with a consensus rate of at least 91% regarding diagnosis, monitoring, and management of ASC in children. A summary flowchart is presented based on daily scoring of the Paediatric Ulcerative Colitis Activity Index. Several topics have been altered since the previous 2011 guidelines and from those published in adults.
DISCUSSION
These guidelines standardize the management of ASC in children in an attempt to optimize outcomes of this intensive clinical scenario.
Acute severe colitis (ASC) is one of the few emergencies in pediatric gastroenterology. Tight monitoring and timely medical and surgical interventions may improve outcomes and minimize morbidity and mortality. We aimed to standardize daily treatment of ASC in children through detailed recommendations and practice points which are based on a systematic review of the literature and consensus of experts.
METHODS
These guidelines are a joint effort of the European Crohn's and Colitis Organization (ECCO) and the European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN). Fifteen predefined questions were addressed by working subgroups. An iterative consensus process, including 2 face-to-face meetings, was followed by voting of the national representatives of ECCO and all members of the Paediatric Inflammatory Bowel Disease (IBD) Porto group of ESPGHAN (43 voting experts).
RESULTS
A total of 24 recommendations and 43 practice points were endorsed with a consensus rate of at least 91% regarding diagnosis, monitoring, and management of ASC in children. A summary flowchart is presented based on daily scoring of the Paediatric Ulcerative Colitis Activity Index. Several topics have been altered since the previous 2011 guidelines and from those published in adults.
DISCUSSION
These guidelines standardize the management of ASC in children in an attempt to optimize outcomes of this intensive clinical scenario.
- Language
-
- English
- Open access status
- green
- Identifiers
-
- DOI 10.1097/MPG.0000000000002036
- PMID 30044358
- Persistent URL
- https://folia.unifr.ch/global/documents/135097
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