Genome-wide association study of kidney function decline in individuals of European descent.

• Gorski M 1] Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany [2] Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.
• Tin A Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
• Garnaas M Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
• McMahon GM 1] Division of Nephrology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA [2] NHLBI's Framingham Heart Study, National Heart, Lung and Blood Institute, Framingham, Massachusetts, USA.
• Chu AY Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
• Tayo BO Department of Public Health Services, Loyola Medical Center, Loyola University Chicago, Maywood, Illinois, USA.
• Pattaro C Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Bolzano, Italy.
• Teumer A Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University of Greifswald, Greifswald, Germany.
• Chasman DI Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
• Chalmers J George Institute for Global Health, University of Sydney, Sydney, New South Wales, Australia.
• Hamet P Centre de recherche du Centre hospitalier de l'Université de Montréal, University of Montreal, Montreal, Quebec, Canada.
• Tremblay J CHUM Research Center- Technopôle Angus, Montreal, Québec, Canada.
• Woodward M George Institute for Global Health, University of Sydney, Sydney, New South Wales, Australia.
• Aspelund T 1] Icelandic Heart Association, Research Institute, Kopavogur, Iceland [2] University of Iceland, Reykjavik, Iceland.
• Eiriksdottir G Icelandic Heart Association, Research Institute, Kopavogur, Iceland.
• Gudnason V 1] Icelandic Heart Association, Research Institute, Kopavogur, Iceland [2] University of Iceland, Reykjavik, Iceland.
• Harris TB Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland, USA.
• Launer LJ Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland, USA.
• Smith AV 1] Icelandic Heart Association, Research Institute, Kopavogur, Iceland [2] University of Iceland, Reykjavik, Iceland.
• Mitchell BD 1] Department of Medicine and Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA [2] Geriatric Research and Education Clinical Center, Veterans Administration Medical Center, University of Maryland School of Medicine, Baltimore, Maryland, USA.
• O'Connell JR Department of Medicine and Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.
• Shuldiner AR 1] Department of Medicine and Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA [2] Geriatric Research and Education Clinical Center, Veterans Administration Medical Center, University of Maryland School of Medicine, Baltimore, Maryland, USA.
• Coresh J 1] Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA [2] Welch Center for Prevention, Epidemiology and Clinical Research, Baltimore, Maryland, USA.
• Li M Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
• Freudenberger P Institute of Molecular Biology and Biochemistry, Medical University Graz, Graz, Austria.
• Hofer E Department of Neurology, Institute for Medical Informatics, Statistics and Documentation, Medical University Graz, Graz, Austria.
• Schmidt H Institute of Molecular Biology and Biochemistry, Medical University Graz, Graz, Austria.
• Schmidt R Department of Neurology, Medical University Graz, Graz, Austria.
• Holliday EG Centre for Clinical Epidemiology and Biostatistics, University of Newcastle, CReDITSS, HMRI, Callaghan, New South Wales, Australia.
• Mitchell P Centre for Vision Research, Westmead Millennium Institute, University of Sydney, Westmead Hospital, Sydney, New South Wales, Australia.
• Wang JJ Centre for Vision Research, Westmead Millennium Institute, University of Sydney, Westmead Hospital, Sydney, New South Wales, Australia.
• de Boer IH University of Washington, Seattle, Washington, USA.
• Li G Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA.
• Siscovick DS 1] Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA [2] New York Academy of Medicine, New York, New York, USA.
• Kutalik Z 1] Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland [2] Department of Medical Genetics, Swiss Institute of Bioinformatics, Lausanne, Switzerland.
• Corre T Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland.
• Vollenweider P Internal Medicine Department, Lausanne University Hospital, Lausanne, Switzerland.
• Waeber G Internal Medicine Department, Lausanne University Hospital, Lausanne, Switzerland.
• Gupta J Perelman School of Medicine at the University of Pennsylvania, Center for Clinical Epidemiology and Biostatistics.
• Kanetsky PA Perelman School of Medicine at the University of Pennsylvania, Center for Clinical Epidemiology and Biostatistics.
• Hwang SJ NHLBI's Framingham Heart Study, National Heart, Lung and Blood Institute, Framingham, Massachusetts, USA.
• Olden M 1] Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany [2] NHLBI's Framingham Heart Study, National Heart, Lung and Blood Institute, Framingham, Massachusetts, USA.
• Yang Q 1] NHLBI's Framingham Heart Study, National Heart, Lung and Blood Institute, Framingham, Massachusetts, USA [2] Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.
• de Andrade M Mayo Clinic, Rochester, Minnesota, USA.
• Atkinson EJ Mayo Clinic, Rochester, Minnesota, USA.
• Kardia SL University of Michigan, Ann Arbor, Michigan, USA.
• Turner ST Mayo Clinic, Rochester, Minnesota, USA.
• Stafford JM Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
• Ding J Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
• Liu Y Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
• Barlassina C Department of Health Science, University of Milano, Milano, Italy.
• Cusi D 1] Department of Health Science, University of Milano, Milano, Italy [2] Division of Nephrology, San Paolo Hospital, Milano, Italy.
• Salvi E Department of Health Science, University of Milano, Milano, Italy.
• Staessen JA 1] Department of Epidemiology, Maastricht University, Maastricht, The Netherlands [2] Studies Coordinating Centre, Division of Hypertension and Cardiovascular Rehabilitation, Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium.
• Ridker PM Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
• Grallert H 1] Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany [2] Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany [3] German Center for Diabetes Research, Neuherberg, Germany.
• Meisinger C Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
• Müller-Nurasyid M 1] DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany [2] Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany [3] Institute of Medical Informatics, Biometry, and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany [4] Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany.
• Krämer BK University Medical Centre Mannheim, 5th Department of Medicine, University of Heidelberg, Mannheim, Germany.
• Kramer H Department of Public Health Services, Loyola Medical Center, Loyola University Chicago, Maywood, Illinois, USA.
• Rosas SE Joslin Diabetes Center and Beth Israel Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
• Nolte IM 1] Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands [2] Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology (FA40), University Medical Center Groningen, Groningen, The Netherlands.
• Penninx BW 1] Department of Psychiatry/EMGO Institute/Neuroscience Campus, VU University Medical Centre, Amsterdam, The Netherlands [2] EMGO Institute Vumc, NESDA, Amsterdam, The Netherlands.
• Snieder H 1] Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands [2] Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology (FA40), University Medical Center Groningen, Groningen, The Netherlands.
• Fabiola Del Greco M Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Bolzano, Italy.
• Franke A Institute of Clinical Molecular Biology, Kiel, Germany.
• Nöthlings U 1] Popgen Biobank, University Hospital Schleswig-Holstein, Kiel, Germany [2] Section for Epidemiology, Institute for Experimental Medicine, Christian-Albrechts-University of Kiel, Kiel, Germany.
• Lieb W Institute of Epidemiology and Biobank popgen, Christian-Albrechts University, Kiel, Germany.
• Bakker SJ University Medical Center Groningen, Department of Nephrology, University of Groningen, Groningen, The Netherlands.
• Gansevoort RT University Medical Center Groningen, Department of Nephrology, University of Groningen, Groningen, The Netherlands.
• van der Harst P University Medical Center Groningen, Department of Cardiology, University of Groningen, Groningen, The Netherlands.
• Dehghan A Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
• Franco OH Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
• Hofman A Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
• Rivadeneira F Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
• Sedaghat S Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
• Uitterlinden AG Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
• Coassin S Division of Genetic Epidemiology, Innsbruck Medical University, Innsbruck, Austria.
• Haun M Division of Genetic Epidemiology, Innsbruck Medical University, Innsbruck, Austria.
• Kollerits B Division of Genetic Epidemiology, Innsbruck Medical University, Innsbruck, Austria.
• Kronenberg F Division of Genetic Epidemiology, Innsbruck Medical University, Innsbruck, Austria.
• Paulweber B First Department of Internal Medicine, Paracelsus Private Medical University Salzburg, Salzburg, Austria.
• Aumann N Department SHIP/KEF, Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.
• Endlich K Institute of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald, Germany.
• Pietzner M Institute for Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.
• Völker U Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University of Greifswald, Greifswald, Germany.
• Rettig R Institute of Physiology, University of Greifswald, Greifswald-Karlsburg, Germany.
• Chouraki V Inserm, U744, Institut Pasteur de Lille, Université Lille-Nord de France, CHR&U de Lille, Service d'épidémiologie régional, CHRU, Lille, France.
• Helmer C Inserm, U897, Université Bordeaux 2, ISPED, ISPED, Université Bordeaux 2, Bordeaux, France.
• Lambert JC Inserm, U744, Institut Pasteur de Lille, Université Lille-Nord de France, Institut Pasteur, Lille, France.
• Metzger M Inserm, U1018, University Paris-Sud, CESP Team 10, Villejuif, France.
• Stengel B Inserm, U1018, University Paris-Sud, CESP Team 10, Villejuif, France.
• Lehtimäki T Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.
• Lyytikäinen LP Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.
• Raitakari O 1] Department of Clinical Physiology, Turku University Hospital, Turku, Finland [2] Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.
• Johnson A NHLBI Cardiovascular Epidemiology and Human Genomics Branch, Framingham Heart Study, National Heart, Lung and Blood Institute, Framingham, Massachusetts, USA.
• Parsa A Department of Medicine and Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.
• Bochud M Institute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital, Epalinges, Switzerland.
• Heid IM 1] Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany [2] Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
• Goessling W 1] Divisions of Genetics and Gastroenterology, Department of Medicine, Brigham and Women's Hospital, and Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA [2] Harvard Stem Cell Institute, Harvard University and Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
• Köttgen A 1] Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA [2] Renal Division, Freiburg University Clinic, Germany, Freiburg, Germany.
• Kao WH 1] Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA [2] Welch Center for Prevention, Epidemiology and Clinical Research, Baltimore, Maryland, USA.
• Fox CS 1] NHLBI's Framingham Heart Study, National Heart, Lung and Blood Institute, Framingham, Massachusetts, USA [2] Department of Endocrinology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
• Böger CA Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.

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Animals

Cadherins

European Continental Ancestry Group

Genome, Human

Genome-Wide Association Study

Glomerular Filtration Rate

Humans

N-Acetylgalactosaminyltransferases

Renal Insufficiency

Uromodulin