Scalable, Economical, and Practical Synthesis of 4-(Difluoromethyl)pyridin-2-amine, a Key Intermediate for Lipid Kinase Inhibitors
- Rageot, Denise ORCID Department of Biomedicine, University of Basel, Mattenstrasse 28, 4058 Basel, Switzerland
- Beaufils, Florent PIQUR Therapeutics AG, Hochbergerstrasse 60, 4057 Basel, Switzerland
- Borsari, Chiara ORCID Department of Biomedicine, University of Basel, Mattenstrasse 28, 4058 Basel, Switzerland
- Dall’Asen, Alix PIQUR Therapeutics AG, Hochbergerstrasse 60, 4057 Basel, Switzerland
- Neuburger, Markus Department of Chemistry, University of Basel, St. Johanns-Ring 19, 4056 Basel, Switzerland
- Hebeisen, Paul PIQUR Therapeutics AG, Hochbergerstrasse 60, 4057 Basel, Switzerland
- Wymann, Matthias P. ORCID Department of Biomedicine, University of Basel, Mattenstrasse 28, 4058 Basel, Switzerland
- 2019-9-25
Published in:
- Organic Process Research & Development. - American Chemical Society (ACS). - 2019, vol. 23, no. 11, p. 2416-2424
- Language
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- English
- Open access status
- hybrid
- Identifiers
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- DOI 10.1021/acs.oprd.9b00312
- ISSN 1083-6160
- Persistent URL
- https://folia.unifr.ch/global/documents/11330
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