Evidence for Tocilizumab as a Treatment Option in Refractory Uveitis Associated with Juvenile Idiopathic Arthritis.

• Tappeiner C From the Department of Ophthalmology, St. Franziskus Hospital, Münster; Department of Ophthalmology and Interdisciplinary Uveitis Center, University of Heidelberg, Heidelberg; University of Duisburg-Essen, Essen, Germany; Department of Ophthalmology, Inselspital, University of Bern, Bern, Switzerland; Institut Clinic d'Oftalmologia, Hospital Clínic de Barcelona, University of Barcelona; Pediatric Rheumatology Unit, and Ophthalmology Department, Hospital Sant Joan de Déu, University of Barcelona, Esplugues, Barcelona, Spain; Department of Paediatric Rheumatology, Bristol Royal Hospital for Children; Clinical Research Unit, Bristol Eye Hospital, Bristol, UK; Department of Ophthalmology, Helsinki University Hospital, Helsinki, Finland; Department of Ophthalmology, University Medical Center Utrecht, Utrecht, the Netherlands. christoph.tappeiner@insel.ch.
• Mesquida M From the Department of Ophthalmology, St. Franziskus Hospital, Münster; Department of Ophthalmology and Interdisciplinary Uveitis Center, University of Heidelberg, Heidelberg; University of Duisburg-Essen, Essen, Germany; Department of Ophthalmology, Inselspital, University of Bern, Bern, Switzerland; Institut Clinic d'Oftalmologia, Hospital Clínic de Barcelona, University of Barcelona; Pediatric Rheumatology Unit, and Ophthalmology Department, Hospital Sant Joan de Déu, University of Barcelona, Esplugues, Barcelona, Spain; Department of Paediatric Rheumatology, Bristol Royal Hospital for Children; Clinical Research Unit, Bristol Eye Hospital, Bristol, UK; Department of Ophthalmology, Helsinki University Hospital, Helsinki, Finland; Department of Ophthalmology, University Medical Center Utrecht, Utrecht, the Netherlands.
• Adán A From the Department of Ophthalmology, St. Franziskus Hospital, Münster; Department of Ophthalmology and Interdisciplinary Uveitis Center, University of Heidelberg, Heidelberg; University of Duisburg-Essen, Essen, Germany; Department of Ophthalmology, Inselspital, University of Bern, Bern, Switzerland; Institut Clinic d'Oftalmologia, Hospital Clínic de Barcelona, University of Barcelona; Pediatric Rheumatology Unit, and Ophthalmology Department, Hospital Sant Joan de Déu, University of Barcelona, Esplugues, Barcelona, Spain; Department of Paediatric Rheumatology, Bristol Royal Hospital for Children; Clinical Research Unit, Bristol Eye Hospital, Bristol, UK; Department of Ophthalmology, Helsinki University Hospital, Helsinki, Finland; Department of Ophthalmology, University Medical Center Utrecht, Utrecht, the Netherlands.
• Anton J From the Department of Ophthalmology, St. Franziskus Hospital, Münster; Department of Ophthalmology and Interdisciplinary Uveitis Center, University of Heidelberg, Heidelberg; University of Duisburg-Essen, Essen, Germany; Department of Ophthalmology, Inselspital, University of Bern, Bern, Switzerland; Institut Clinic d'Oftalmologia, Hospital Clínic de Barcelona, University of Barcelona; Pediatric Rheumatology Unit, and Ophthalmology Department, Hospital Sant Joan de Déu, University of Barcelona, Esplugues, Barcelona, Spain; Department of Paediatric Rheumatology, Bristol Royal Hospital for Children; Clinical Research Unit, Bristol Eye Hospital, Bristol, UK; Department of Ophthalmology, Helsinki University Hospital, Helsinki, Finland; Department of Ophthalmology, University Medical Center Utrecht, Utrecht, the Netherlands.
• Ramanan AV From the Department of Ophthalmology, St. Franziskus Hospital, Münster; Department of Ophthalmology and Interdisciplinary Uveitis Center, University of Heidelberg, Heidelberg; University of Duisburg-Essen, Essen, Germany; Department of Ophthalmology, Inselspital, University of Bern, Bern, Switzerland; Institut Clinic d'Oftalmologia, Hospital Clínic de Barcelona, University of Barcelona; Pediatric Rheumatology Unit, and Ophthalmology Department, Hospital Sant Joan de Déu, University of Barcelona, Esplugues, Barcelona, Spain; Department of Paediatric Rheumatology, Bristol Royal Hospital for Children; Clinical Research Unit, Bristol Eye Hospital, Bristol, UK; Department of Ophthalmology, Helsinki University Hospital, Helsinki, Finland; Department of Ophthalmology, University Medical Center Utrecht, Utrecht, the Netherlands.
• Carreno E From the Department of Ophthalmology, St. Franziskus Hospital, Münster; Department of Ophthalmology and Interdisciplinary Uveitis Center, University of Heidelberg, Heidelberg; University of Duisburg-Essen, Essen, Germany; Department of Ophthalmology, Inselspital, University of Bern, Bern, Switzerland; Institut Clinic d'Oftalmologia, Hospital Clínic de Barcelona, University of Barcelona; Pediatric Rheumatology Unit, and Ophthalmology Department, Hospital Sant Joan de Déu, University of Barcelona, Esplugues, Barcelona, Spain; Department of Paediatric Rheumatology, Bristol Royal Hospital for Children; Clinical Research Unit, Bristol Eye Hospital, Bristol, UK; Department of Ophthalmology, Helsinki University Hospital, Helsinki, Finland; Department of Ophthalmology, University Medical Center Utrecht, Utrecht, the Netherlands.
• Mackensen F From the Department of Ophthalmology, St. Franziskus Hospital, Münster; Department of Ophthalmology and Interdisciplinary Uveitis Center, University of Heidelberg, Heidelberg; University of Duisburg-Essen, Essen, Germany; Department of Ophthalmology, Inselspital, University of Bern, Bern, Switzerland; Institut Clinic d'Oftalmologia, Hospital Clínic de Barcelona, University of Barcelona; Pediatric Rheumatology Unit, and Ophthalmology Department, Hospital Sant Joan de Déu, University of Barcelona, Esplugues, Barcelona, Spain; Department of Paediatric Rheumatology, Bristol Royal Hospital for Children; Clinical Research Unit, Bristol Eye Hospital, Bristol, UK; Department of Ophthalmology, Helsinki University Hospital, Helsinki, Finland; Department of Ophthalmology, University Medical Center Utrecht, Utrecht, the Netherlands.
• Kotaniemi K From the Department of Ophthalmology, St. Franziskus Hospital, Münster; Department of Ophthalmology and Interdisciplinary Uveitis Center, University of Heidelberg, Heidelberg; University of Duisburg-Essen, Essen, Germany; Department of Ophthalmology, Inselspital, University of Bern, Bern, Switzerland; Institut Clinic d'Oftalmologia, Hospital Clínic de Barcelona, University of Barcelona; Pediatric Rheumatology Unit, and Ophthalmology Department, Hospital Sant Joan de Déu, University of Barcelona, Esplugues, Barcelona, Spain; Department of Paediatric Rheumatology, Bristol Royal Hospital for Children; Clinical Research Unit, Bristol Eye Hospital, Bristol, UK; Department of Ophthalmology, Helsinki University Hospital, Helsinki, Finland; Department of Ophthalmology, University Medical Center Utrecht, Utrecht, the Netherlands.
• de Boer JH From the Department of Ophthalmology, St. Franziskus Hospital, Münster; Department of Ophthalmology and Interdisciplinary Uveitis Center, University of Heidelberg, Heidelberg; University of Duisburg-Essen, Essen, Germany; Department of Ophthalmology, Inselspital, University of Bern, Bern, Switzerland; Institut Clinic d'Oftalmologia, Hospital Clínic de Barcelona, University of Barcelona; Pediatric Rheumatology Unit, and Ophthalmology Department, Hospital Sant Joan de Déu, University of Barcelona, Esplugues, Barcelona, Spain; Department of Paediatric Rheumatology, Bristol Royal Hospital for Children; Clinical Research Unit, Bristol Eye Hospital, Bristol, UK; Department of Ophthalmology, Helsinki University Hospital, Helsinki, Finland; Department of Ophthalmology, University Medical Center Utrecht, Utrecht, the Netherlands.
• Bou R From the Department of Ophthalmology, St. Franziskus Hospital, Münster; Department of Ophthalmology and Interdisciplinary Uveitis Center, University of Heidelberg, Heidelberg; University of Duisburg-Essen, Essen, Germany; Department of Ophthalmology, Inselspital, University of Bern, Bern, Switzerland; Institut Clinic d'Oftalmologia, Hospital Clínic de Barcelona, University of Barcelona; Pediatric Rheumatology Unit, and Ophthalmology Department, Hospital Sant Joan de Déu, University of Barcelona, Esplugues, Barcelona, Spain; Department of Paediatric Rheumatology, Bristol Royal Hospital for Children; Clinical Research Unit, Bristol Eye Hospital, Bristol, UK; Department of Ophthalmology, Helsinki University Hospital, Helsinki, Finland; Department of Ophthalmology, University Medical Center Utrecht, Utrecht, the Netherlands.
• de Vicuña CG From the Department of Ophthalmology, St. Franziskus Hospital, Münster; Department of Ophthalmology and Interdisciplinary Uveitis Center, University of Heidelberg, Heidelberg; University of Duisburg-Essen, Essen, Germany; Department of Ophthalmology, Inselspital, University of Bern, Bern, Switzerland; Institut Clinic d'Oftalmologia, Hospital Clínic de Barcelona, University of Barcelona; Pediatric Rheumatology Unit, and Ophthalmology Department, Hospital Sant Joan de Déu, University of Barcelona, Esplugues, Barcelona, Spain; Department of Paediatric Rheumatology, Bristol Royal Hospital for Children; Clinical Research Unit, Bristol Eye Hospital, Bristol, UK; Department of Ophthalmology, Helsinki University Hospital, Helsinki, Finland; Department of Ophthalmology, University Medical Center Utrecht, Utrecht, the Netherlands.
• Heiligenhaus A From the Department of Ophthalmology, St. Franziskus Hospital, Münster; Department of Ophthalmology and Interdisciplinary Uveitis Center, University of Heidelberg, Heidelberg; University of Duisburg-Essen, Essen, Germany; Department of Ophthalmology, Inselspital, University of Bern, Bern, Switzerland; Institut Clinic d'Oftalmologia, Hospital Clínic de Barcelona, University of Barcelona; Pediatric Rheumatology Unit, and Ophthalmology Department, Hospital Sant Joan de Déu, University of Barcelona, Esplugues, Barcelona, Spain; Department of Paediatric Rheumatology, Bristol Royal Hospital for Children; Clinical Research Unit, Bristol Eye Hospital, Bristol, UK; Department of Ophthalmology, Helsinki University Hospital, Helsinki, Finland; Department of Ophthalmology, University Medical Center Utrecht, Utrecht, the Netherlands.

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BIOLOGICS

CYSTOID MACULAR EDEMA

JUVENILE IDIOPATHIC ARTHRITIS

TOCILIZUMAB

UVEITIS

Adolescent

Antibodies, Monoclonal, Humanized

Antirheumatic Agents

Arthritis, Juvenile

Child

Female

Humans

Immunosuppressive Agents

Male

Methotrexate

Retreatment

Retrospective Studies

Treatment Outcome

Uveitis

Young Adult